Catalytic Enantioselective Electrophilic α‐Amination of β‐Ketoesters Catalyzed by Chiral Palladium Complexes.
Catalytic Enantioselective Electrophilic α‐Amination of β‐Ketoesters Catalyzed by Chiral Palladium Complexes.
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DOI：
10.1002/chin.200642186
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发表时间：
2006-07
期刊：
影响因子：
--
通讯作者：
Young Ku Kang;D. Kim
中科院分区：
文献类型：
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作者：
Young Ku Kang;D. Kim
The catalytic enantioselective electrophilic α-amination promoted chiral palladium complexes is described. Treatment of β-ketoesters with azodicarboxylates as electrophilic amination reagents under mild reaction conditions afforded the corresponding α-amino β-ketoesters with excellent enantiomeric excesses (91–99% ee). Palladium complexes were immobilized in [bmim]PF6, and their applications to catalytic α-amination of β-ketoesters were successfully demonstrated.
