Antimicrobial resistance in Salmonella isolates from apparently healthy food-producing animal from 2000 to 2003:: The first stage of Japanese Veterinary Antimicrobial Resistance Monitoring (JVARM)
Antimicrobial resistance in Salmonella isolates from apparently healthy food-producing animal from 2000 to 2003:: The first stage of Japanese Veterinary Antimicrobial Resistance Monitoring (JVARM)
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DOI：
10.1292/jvms.68.881
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发表时间：
2006-08-01
影响因子：
1.2
通讯作者：
Takahashi, Toshio
中科院分区：
文献类型：
--
作者：
Asai, Tetsuo;Esaki, Hidetake;Takahashi, Toshio
从2000年至2003年期间在日本各地获得的表面健康的食品生产动物的183沙门氏菌分离株的抗菌药物敏感性进行了检查。在29个血清型中，以婴儿沙门氏菌（37.7%）最常见，其次是沙门氏菌。鼠伤寒（19.7%）。对双氢链霉素耐药的沙门氏菌（77.6%）比对土霉素耐药的沙门氏菌（67.8%）高出约10%，尽管在日本，四环素类抗生素的国家级兽医使用远远高于链霉素。在17株（9.3%）耐萘啶酸的菌株中，在gyrA基因喹诺酮类耐药决定区的84或87处检测到单点突变。
Antimicrobial susceptibility of 183 Salmonella isolates from apparently healthy food-producing animals obtained during the period from 2000 to 2003 throughout Japan was examined. Of 29 serovars identified, Salmonella Infantis (37.7%) was the most prevalent, followed by S. Typhimurium (19.7%). Salmonella bacteria resistant to dihydrostreptomycin (77.6%) were about 10% more prevalent than those resistant to oxytetracycline (67.8%), though the nation-level veterinary use of tetracycline antibiotics is much greater than that of streptomycin in Japan. In seventeen isolates (9.3%) resistant to nalidixic acid, single point mutations were detected at 84 or 87 in the quinolone resistance-determining region of the gyrA gene.