Relaxin levels in the maternal plasma of pigs before, during, and after parturition and before, during, and after suckling.
Relaxin levels in the maternal plasma of pigs before, during, and after parturition and before, during, and after suckling.
复制标题
猪在分娩前、分娩过程中和分娩后以及哺乳前、哺乳期间和哺乳后母体血浆中松弛素的水平。
DOI：
10.1095/biolreprod25.1.65
复制
发表时间：
1981
影响因子：
3.6
通讯作者：
Rutherford,JE
中科院分区：
文献类型：
--
作者：
Sherwood,OD;Nara,BS;Welk,FA;First,NL;Rutherford,JE
在母猪分娩前、分娩期间和分娩后，以及哺乳前、哺乳期间和哺乳后，对母猪外周血浆中松弛素浓度进行了频繁的测定。松弛素浓度从妊娠第110天0400h的2.7 ng/ml稳定上升到妊娠第112天2400h的15.8 ng/ml。在分娩前的两天内，松弛素水平显著增加。在几乎所有的猪中，松弛素水平的这种产前升高包括两到三个持续的高峰，持续10到20小时，在分娩前大约15小时达到最大松弛素浓度，范围从42到257 ng/ml。分娩后37小时，血浆松弛素值持续下降，平均为0.4 ng/ml。在分娩期间，松弛素水平相对稳定，不超过分娩前立即观察到的水平。在哺乳期第7天、第14天、第21天和第28天检查的七头母猪中，没有一头在哺乳前、哺乳期间或哺乳后的血浆中检测到松弛素。在这些猪中，只有4头在哺乳第3天检测到松弛素，这些猪的松弛素水平仅为0.1-0.4 ng/ml，不受哺乳的影响。
Relaxin concentrations in peripheral plasma have been measured at frequent intervals before, during, and after parturition and before, during, and after suckling in maternal pigs. Relaxin concentrations rose steadily from 2.7 ng/ml at 0400 h on Day 110 to 15.8 ng/ml at 2400 h on Day 112 of pregnancy. During the 2 days which preceded parturition, there was a marked increase in relaxin levels. In nearly all pigs this prepartum elevation in relaxin levels consisted of two or three sustained surges which lasted for 10 to 20 h. Maximal relaxin concentrations, which ranged from 42 to 257 ng/ml, were obtained approximately 15 h before parturition. This maximum was followed by a sustained decrease in plasma relaxin levels to a mean of 0.4 ng/ml by 37 h after parturition. During parturition relaxin levels were relatively constant and did not exceed those observed immediately before parturition. Relaxin was not detected before, during, or after suckling in the plasma of any of the seven maternal pigs examined on Days 7, 14, 21, and 28 of lactation. Only in four of these pigs was relaxin detected on Day 3 of lactation, and in these cases relaxin levels were only 0.1 to 0.4 ng/ml and were not influenced by suckling.