Nanocrystallization Mechanism of Organic Compounds in the Reprecipitation Method by Stopped-Flow Analysis
Nanocrystallization Mechanism of Organic Compounds in the Reprecipitation Method by Stopped-Flow Analysis
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DOI：
10.1143/jjap.48.105003
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发表时间：
2009-10-01
影响因子：
1.5
通讯作者：
Nakanishi, Hachiro
中科院分区：
文献类型：
--
作者：
Oliveira, Daniel;Baba, Koichi;Nakanishi, Hachiro
纳米粒子形成的再沉淀法为三种不同类型的芳香族化合物进行了研究，通过监测诱导的光谱变化，使用停流技术。在不同的条件下，作为温度，浓度，和溶剂的类型进行了系统的变化，纳米化的速率进行了测定。定性地证明，在毫秒量级上，晶体生长受经典成核理论支配。据发现，过饱和比，并因此在水/有机溶剂混合物中的有机化合物的溶解度，是理解有机纳米颗粒形成的动力学的关键因素。因此，当控制纳米颗粒形成时，仔细控制过饱和比是至关重要的。(C)2009日本应用物理学会
Nanoparticle formation by the reprecipitation method for three different types of aromatic compounds was investigated by monitoring induced spectral changes using the stopped-flow technique. The rate of nanocrystallization was determined under different conditions, as temperature, concentration, and type of solvent were systematically varied. It turned out qualitatively that on the millisecond order, nanocrystal growth is governed by the classical nucleation theory. It was found that the supersaturation ratio, and thus the solubility of the organic compound in a water/organic solvent mixture, is a key factor in understanding the kinetics of organic nanoparticle formation. Therefore, careful control of the supersaturation ratio is critical when controlling nanoparticle formation. (C) 2009 The Japan Society of Applied Physics