The biology of chronically denervated Schwann cells
The biology of chronically denervated Schwann cells
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DOI：
10.1111/j.1749-6632.1999.tb08584.x
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发表时间：
1999-01-01
期刊：
影响因子：
--
通讯作者：
Hall, SM
中科院分区：
文献类型：
--
作者：
Hall, SM
本文分为两部分，均涉及慢性去神经支配对雪旺细胞的影响。第一组实验探讨了长时间去神经支配在体内雪旺细胞中产生损害轴突再生的变化的提议。第二组实验比较了体外急性和慢性失神经雪旺细胞的分子表型，并检查了它们对外源性神经调节蛋白的反应。
This paper is divided into two sections, both concerned with the effects of chronic denervation on Schwann cells. The first group of experiments explore the proposal that lengthy denervation produces changes in Schwann cells in vivo that compromise axonal regeneration. The second group of experiments compare the molecular phenotypes of acutely and chronically denervated Schwann cells in vitro, and examine their responses to an exogenously applied neuregulin.