Pathogenesis of peptic ulcer and implications for therapy.
Pathogenesis of peptic ulcer and implications for therapy.
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消化性溃疡的发病机制及其对治疗的影响。
DOI：
10.1056/nejm199003293221307
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
Soll,AH
中科院分区：
文献类型：
--
作者：
Soll,AH
尽管消化性溃疡的几个特征在过去几年中得到了阐明，但新的问题已经取代了那些已经回答的问题。一些可能使人们易患消化性溃疡的因素已经被确定，但它们如何产生影响以及如何在治疗上与之斗争仍不清楚。本研讨会简要回顾了目前关于消化性溃疡发病机制的知识，并讨论了治疗策略。正常胃十二指肠粘膜对酸和消化性损伤的防御三个基本水平的防御基础正常胃十二指肠粘膜抵抗酸和消化性损伤的显着能力。
ALTHOUGH several features of peptic ulcer disease have been elucidated over the past few years, new questions have replaced those that have been answered. Some of the factors that may predispose people to the development of peptic ulcers have been identified, but how they produce their effects and how they can be combated therapeutically remain unclear. This seminar briefly reviews current knowledge about the pathogenesis of peptic ulcers and discusses strategies for treatment.Defense of Normal Mucosa against Acid and Peptic InjuryThree basic levels of defense underlie the remarkable ability of normal gastroduodenal mucosa to resist injury from the . . .