Curry leaf (Murraya koenigii Spreng.) reduces blood cholesterol and glucose levels in ob/ob mice.
Curry leaf (Murraya koenigii Spreng.) reduces blood cholesterol and glucose levels in ob/ob mice.
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咖喱叶（Murraya koenigii Spreng.）可降低 ob/ob 小鼠的血液胆固醇和血糖水平。
DOI：
10.1142/s0192415x06003825
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发表时间：
2006
期刊：
影响因子：
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通讯作者：
Yuan,Chun-Su
中科院分区：
文献类型：
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作者：
Xie,Jing-Tian;Chang,Wei-Tien;Wang,Chong-Zhi;Mehendale,SangeetaR;Li,Jing;Ambihaipahar,Ramalingam;Ambihaipahar,Umadevi;Fong,HarryH;Yuan,Chun-Su
We observed that curry leaf (Murraya koenigii) extract possesses the property to decrease blood cholesterol and blood glucose levels in diabeticob/obmice. Mice received daily intraperitoneal injections of 80 mg/kg curry leaf extract for 10 consecutive days. The extract significantly decreased blood cholesterol level from 277.6 ± 16.6 mg/d (day 0) to 182.0 ± 15.3 mg/d (day 10, p < 0.01 compared with the change in vehicle group). The extract also significantly decreased blood glucose level from 387.0 ± 15.6 mg/dl (day 0) to 214.0 ± 26.6 mg/dl (day 10, p < 0.01). In addition, body weight was reduced after extract treatment. Our data suggest that curry leaf may be proved to be of clinical importance in improving the management of high cholesterol level and type 2 diabetes.
