A new Vilsmeier-type reaction for one-pot synthesis of pH sensitive fluorescent cyanine dyes
A new Vilsmeier-type reaction for one-pot synthesis of pH sensitive fluorescent cyanine dyes
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DOI：
10.1016/j.tet.2006.05.063
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发表时间：
2006-08-14
期刊：
影响因子：
2.1
通讯作者：
Almeida, Paulo
中科院分区：
文献类型：
--
作者：
EI-Shishtawy, Reda M.;Almeida, Paulo
提出了一种新的维斯迈耶型反应，用于合成新型吲哚碳菁pH传感器，该传感器在质子化时具有荧光，但在质子提取时不具有荧光。当ph值随pK(a)值接近中性而发生细微变化时，这些传感器显示出显著的比例紫外可见光谱和荧光光谱变化。(c) 2006 Elsevier Ltd.版权所有。
A new Vilsmeier-type reaction is suggested for the synthesis of novel indocarbocyanine pH sensors, which are fluorescent when protonated but nonfluorescent upon proton abstraction. These sensors show significant ratiometric UV-visible as well as fluorescence spectral changes upon subtle variation of pHs with pK(a) values near neutral. (c) 2006 Elsevier Ltd. All rights reserved.