Decrease of motor cortex excitability following exposure to a 20 Hz magnetic field as generated by a rotating permanent magnet
Decrease of motor cortex excitability following exposure to a 20 Hz magnetic field as generated by a rotating permanent magnet
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DOI：
10.1016/j.clinph.2018.03.045
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发表时间：
2018-07-01
影响因子：
4.7
通讯作者：
Christova, Monica
中科院分区：
文献类型：
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作者：
Gallasch, Eugen;Rafolt, Dietmar;Christova, Monica
目的：静态磁体在运动皮层（MC）上的旋转产生经颅交变磁场（tAMF）和链接的交变电场。本研究的目的是探讨经颅磁刺激（TMS）的领域是否能够影响MC的兴奋性，以及是否有平行tACS诱导effects.Methods：14名健康志愿者接受20 Hz tAMF刺激的MC，在顶点，和20 Hz tACS的MC，每个持续时间为15 min。TMS评估之前和之后的干预措施进行。结果：tACS和tAMF刺激MC对皮层兴奋性的影响是不同的。tAMF刺激后MEP波幅和ICF降低，SICI的作用增强。后tACS MEP幅度增加，有没有影响SICI和ICF.Conclusions：记录的单脉冲和成对脉冲MEP表明MC兴奋性普遍下降以下15毫米tAMF stimulation.Significance：的影响表明，基于旋转磁铁的设备是潜在的适合成为一种新的脑刺激工具，在临床神经生理学。(C)2018国际临床神经生理学联合会。Elsevier B.V.出版，保留所有权利。
Objectives: Rotation of a static magnet over the motor cortex (MC) generates a transcranial alternating magnetic field (tAMF), and a linked alternating electrical field. The aim of this transcranial magnetic stim-ulation (TMS) study is to investigate whether such fields are able to influence MC excitability, and whether there are parallels to tACS induced effects.Methods: Fourteen healthy volunteers received 20 Hz tAMF stimulation over the MC, over the vertex, and 20 Hz tACS over the MC, each with a duration of 15 min. TMS assessments were performed before and after the interventions. Changes in motor evoked potentials (MEP), short interval intra-cortical inhibition (SICI) and intra-cortical facilitation (ICF) were evaluated.Results: The tACS and the tAMF stimulation over the MC affected cortical excitability in a different way. After tAMF stimulation MEP amplitudes and ICF decreased and the effect of SICI increased. After tACS MEP amplitudes increased and there were no effects on SICI and ICF.Conclusions: The recorded single and paired pulse MEPs indicate a general decrease of MC excitability fol-lowing 15 mm of tAMF stimulation.Significance: The effects demonstrate that devices based on rotating magnets are potentially suited to become a novel brain stimulation tool in clinical neurophysiology. (C) 2018 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.