Heterogeneity in Center Practices in Liver Transplantation for Alcohol-Associated Liver Disease in the United States
Heterogeneity in Center Practices in Liver Transplantation for Alcohol-Associated Liver Disease in the United States
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DOI：
10.14309/ajg.0000000000001863
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发表时间：
2022-09-01
影响因子：
9.8
通讯作者：
Desai, Archita P.
中科院分区：
文献类型：
--
作者：
Lim, Nicholas;Kwong, Allison J.;Desai, Archita P.
引言：酒精相关性肝病（ALD）现在是美国（US）肝移植（LT）的主要适应症。目前尚不清楚中心是如何管理的医疗和心理社会问题与这些patient.METHODS：我们进行了一项基于网络的调查LT中心在美国，以确定中心级的细节围LT管理ALDandrelated issues.RESULTS：在117成人LT中心，100个答复（85.5%）收集，代表所有器官采购和移植网络地区。对于酒精相关性肝硬化，70.0%的中心报告没有最低清醒要求，而21.0%的中心需要6个月的清醒。在85.0%的中心进行了重度酒精相关性肝炎的LT。监测协议前LT和LT后酒精使用centers.Discussion不同：我们的研究结果突出了对LT ALD，特别是严重的酒精相关性肝炎中心的态度的变化。
INTRODUCTION: Alcohol-related liver disease (ALD) is now the leading indication for liver transplantation (LT) in the United States (US). It remains unclear how centers are managing the medical and psychosocial issues associated with these patients.METHODS: We conducted a web-based survey of LT centers in the United States to identify center-level details on peri-LT management of ALD and related issues.RESULTS: Of the 117 adult LT centers, 100 responses (85.5%) were collected, representing all Organ Procurement and Transplantation Network regions. For alcohol-associated cirrhosis, 70.0% of the centers reported no minimum sobriety requirement while 21.0% required 6 months of sobriety. LT for severe alcohol-associated hepatitis was performed at 85.0% of the centers. Monitoring protocols for pre-LT and post-LT alcohol use varied among centers.DISCUSSION: Our findings highlight a change in center attitudes toward LT for ALD, particularly for severe alcoholassociated hepatitis.