Transition Metal Catalysis in Aerobic Alcohol Oxidation
Transition Metal Catalysis in Aerobic Alcohol Oxidation
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DOI：
10.1039/9781782621652
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
F. Cardona;C. Parmeggiani
中科院分区：
文献类型：
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作者：
F. Cardona;C. Parmeggiani
为了将原料转化为精细化学品和高价值的积木，可靠的氧化方法已被发现是现代有机合成中不可或缺的工具。1-6已经为各种氧化转化开发了各种高效的方法，这些方法现在已经得到了很好的证实。然而，由于这些标准议定书大多依赖于有害终端氧化剂的使用或造成大量废物的产生，在环境和经济问题上仍明显需要改进方法。特别是在最大限度地减少废物和使用可再生材料方面，催化好氧转化提供了走向可持续发展的“绿色”过程的一些理想特征。特别是，醇的氧化是有机化学实验室和化学工业中最重要的合成操作之一。虽然经典的氧化反应可以非常有效和选择性，但它们往往涉及到化学计量试剂和卤化溶剂的使用，导致产生大量废物。8对更可持续的化学过程的迫切需要
For the conversion of raw materials into fine chemicals and high-value building blocks, reliable oxidation methods have been found to be indispensable tools in modern organic synthesis. 1–6 Various methods with remarkable efficiencies have been developed for a wide array of oxidative transformations which are now well established. However, since most of these standard protocols rely on the use of hazardous terminal oxidants or cause the generation of significant amounts of waste products, there is still an evident need for methodological improvements with respect to environmental and economic issues. Especially in terms of waste product minimization and the use of renewable materials, catalytic aerobic transformations offer some ideal features of a ‘green’process7 towards sustainability. In particular, the oxidation of alcohols is one of the most important synthetic operations in both the organic chemistry laboratory and the chemical industry. Although classic oxidation reactions can be very efficient and selective, they often involve the use of stoichiometric reagents and halogenated solvents, resulting in the generation of large quantities of wastes. 8 The urgent need for more sustainable chemical processes has