The reactivity of the hydrofluorocarbon 1,1,1,2-tetrafluoroethane (HFC-134a) and related compounds towards base attack. The generation and stability of the tetrafluoroethyl, trifluorovinyl and related anions
The reactivity of the hydrofluorocarbon 1,1,1,2-tetrafluoroethane (HFC-134a) and related compounds towards base attack. The generation and stability of the tetrafluoroethyl, trifluorovinyl and related anions
复制标题
DOI：
10.1016/s0022-1139(99)00182-7
复制
发表时间：
1999-11-01
影响因子：
1.9
通讯作者：
Powell, RL
中科院分区：
文献类型：
--
作者：
Burdon, J;Coe, PL;Powell, RL
以1,1,1,2-四氟乙烷为原料，用正丁基锂在-78℃的乙醚中成功合成了三氟乙烯基锂（CF2 = CFLi）。其他碱基（LDA、DBU、MeLi、t-BuLi、t-BuOK）的试验取得了不同程度的成功。该体系的稳定性与温度、浓度和溶剂体系有关。1-氯-2,2,2-三氟乙烷（133a）产生了类似的多氟乙烯锂，但1,1,1-三氟-和1,1,1,2,2,2-六氟乙烷却没有。(C) 1999 Elsevier Science S.A.版权所有
Trifluorovinyllithiun (CF2 = CFLi) has been successfully synthesised from 1,1,1,2-tetrafluoroethane using n-butyllithium at -78 degrees C in ether. Other bases (LDA, DBU, MeLi, t-BuLi, t-BuOK) were tried with varied success. The stability of the system was dependent on temperature, concentration and solvent system employed. 1-Chloro-2,2,2-trifluoroethane (133a) led to an analogous polyfluorovinyllithium, but 1,1,1-trifluoro- and 1,1,1,2,2,2-hexafluoro- ethane did not. (C) 1999 Elsevier Science S.A. All rights reserved.