DOPA-DECARBOXYLASE IN AUTONOMIC AND SENSORY GANGLIA OF CAT
DOPA-DECARBOXYLASE IN AUTONOMIC AND SENSORY GANGLIA OF CAT
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DOI：
10.1111/j.1748-1716.1971.tb04960.x
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发表时间：
1971-01-01
期刊：
影响因子：
--
通讯作者：
NORE, B
中科院分区：
文献类型：
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作者：
GIACOBINI, E;NORE, B
交感神经节多巴胺脱羧酶（DDC）活性可分为3组：腹腔和上级肠系膜活性最高，上级颈和星状神经节居中，腰和骶神经节活性最低。睫状神经节和结状神经节显示出比交感神经节显著更低的DDC活性，并且脊神经节显示出不可测量的活性。DDC活性、单胺氧化酶（MAO）活性与植物神经节中的儿茶酚胺含量之间有良好的相关性。节前去神经支配未显著改变L.r神经节的DDC、MAO或儿茶酚-O-甲基转移酶（COMT）活性。它的结论是，虽然MIAO和DDC是不完全与肾上腺素能神经元，DDC或MAO活性在细胞体中的高水平是肾上腺素能神经元的一个特定属性。
As far as dopadecarboxylase (DDC) activity is concerned sympathetic ganglia can be collected into 3 groups: celiac and superior mesenteric show the highest activity, superior cervical and stellate are intermediate, lumbar and sacral ganglia show the lowest activity. Ciliary and nodose ganglia show significantly lower DDC activity than sympathetic ganglia and spinal ganglia show no measurable activity. There is a good correlation between DDC activities, monoamineoxidase (MAO) activities and the catecholamine contents of autonomic ganglia. Preganglionic de‐nervation did not significantly change DDC, MAO or catechol‐O‐methyltransferase (COMT) activity of L.r ganglia. It is concluded that although MIAO and DDC are not exclusively as sociated with adrenergic neurons, a high level of DDC or MAO activity in the cell body is a specific attribute of adrenergic neurons.