In-Hospital Pneumococcal Polysaccharide Vaccination Is Associated With Detection of Pneumococcal Vaccine Serotypes in Adults Hospitalized for Community-Acquired Pneumonia
In-Hospital Pneumococcal Polysaccharide Vaccination Is Associated With Detection of Pneumococcal Vaccine Serotypes in Adults Hospitalized for Community-Acquired Pneumonia
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DOI：
10.1093/ofid/ofv135
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发表时间：
2015-09-01
影响因子：
4.2
通讯作者：
Self, Wesley H.
中科院分区：
文献类型：
--
作者：
Grijalva, Carlos G.;Wunderink, Richard G.;Self, Wesley H.
在一项对因肺炎住院的成人进行的病原学研究中，我们观察到一些患者在尿液采集前接受了23价肺炎球菌多糖疫苗。一些尿液样本在接种疫苗后不久就对特定的疫苗肺炎球菌血清型呈阳性，这表明假阳性检测结果。
During an etiology study of adults hospitalized for pneumonia, in which urine specimens were examined for serotype-specific pneumococcal antigen detection, we observed that some patients received 23-valent pneumococcal polysaccharide vaccine before urine collection. Some urine samples became positive for specific vaccine pneumococcal serotypes shortly after vaccination, suggesting false-positive test results.