Palladium-Catalyzed Ring-Opening Coupling of Cyclobutenols with Aryl Halides
Palladium-Catalyzed Ring-Opening Coupling of Cyclobutenols with Aryl Halides
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DOI：
10.1055/s-0036-1589117
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发表时间：
2017-10
期刊：
影响因子：
2
通讯作者：
T. Matsuda;Takeshi Matsumoto;A. Murakami
中科院分区：
文献类型：
--
作者：
T. Matsuda;Takeshi Matsumoto;A. Murakami
在钯（0）催化下，叔环丁烯醇与卤代芳烃发生交叉偶联开环反应，生成γ-芳基化β，γ-不饱和酮。在芳基卤化物在邻位带有官能团的情况下，所得开环酮进行分子内缩合，得到双环芳族化合物。
Abstract A palladium(0)-catalyzed ring-opening cross-coupling reaction between tert-cyclobutenols and aryl halides produces γ-arylated β,γ-unsaturated ketones. In the case of aryl halides bearing functional groups at the ortho position, the resulting ring-opened ketones undergo intramolecular condensation to afford bicyclic aromatic compounds.