Comparative assessment of change in fat mass using dual X-ray absorptiometry and air-displacement plethysmography.
Comparative assessment of change in fat mass using dual X-ray absorptiometry and air-displacement plethysmography.
复制标题
使用双 X 射线吸收测定法和空气置换体积描记法对脂肪量变化进行比较评估。
DOI：
10.1111/j.1758-8111.2012.00042.x
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发表时间：
2012
期刊：
影响因子：
3.3
通讯作者：
Buchowski,MaciejS
中科院分区：
文献类型：
--
作者：
Warolin,Joshua;Kantor,Jeff;Whitaker,LaurenE;Choi,Leena;Acra,Sari;Buchowski,MaciejS
•过量脂肪量（FM）被认为是与肥胖相关的健康风险（如心血管、代谢）的主要原因•双X线吸收仪和空气置换体积脉搏描记仪在临床研究和实践中经常用于测量身体成分的变化。•没有公认的单一工具来测量肥胖和FM变化，提供足够准确和精确的估计。•双X线吸收仪（DXA）已证实的准确性支持其作为监测肥胖临床干预相关脂肪量（FM）变化的间接方法。•在识别FM的微小变化方面，DXA比空气置换容积脉搏图更准确。本研究旨在比较双X线吸收仪（DXA）和空气置换体积脉搏图（ADP）测量体成分的准确性，以确定脂肪量（FM）的微小变化。研究纳入56名健康成人，女性29名，男性27名（年龄38±12.4岁，体重指数27.6±5.8 kg m - 2）。排除标准为妊娠、留置金属硬体或起搏器、体重超过DXA表限值（bb0 ~ 350 lb）。所有个体测试均在2小时内完成。脂肪包是用塑料包裹的猪油制成的，并在规定的位置外用。每个参与者都用ADP和DXA完成了身体成分测量（两种测试方式都是在有和没有1公斤外源性FM的情况下完成的）。DXA和ADP在检测外源施加1 kg FM相关的体重总体增加方面都非常准确（分别为0.99 kg和0.97 kg）。与ADP相比，DXA更准确地检测到作为FM的外源性脂肪增加（0.93 kg；差异平均值的90% CI分别为0.83至1.03 kg和0.45 kg； 90% CI分别为0.19至0.71 kg）。男性和女性的体重检测准确性相似（DXA为0.97比1.02，ADP为0.92比1.02），尽管男性检测脂肪增加质量的准确性低于女性（DXA为0.84比1.00，ADP为0.39比0.51）。DXA和ADP在检测外源性1公斤FM相关的体重总体增加方面都是准确的。然而，DXA在正确识别体重增加为FM方面比ADP更准确，而不是无脂体重。
What is already known about this subject•Excess fat mass (FM) is believed to be a primary cause of the health risks (e.g. cardiovascular, metabolic) associated with obesity•Dual X‐ray absorptiometry and air‐displacement plethysmography are frequently used in clinical research and practice to measure body composition changes.•There is no accepted single tool for measurement of obesity and change in FM that provides a sufficiently accurate and precise estimate.What this study adds•The demonstrated accuracy of dual X‐ray absorptiometry (DXA) supports its use as an indirect method for monitoring fat mass (FM) changes associated with clinical interventions for obesity.•DXA is significantly more accurate when compared to air‐displacement plethysmography in recognizing small changes in FM.SummaryThe study aims to compare the accuracy of body composition measurements to small, defined changes in fat mass (FM) between dual X‐ray absorptiometry (DXA) and air‐displacement plethysmography (ADP). Fifty‐six healthy adults, 29 women and 27 men (age, 38 ± 12.4 years; body mass index, 27.6 ± 5.8 kg m−2) were included in the study. Exclusion criteria were pregnancy, indwelling metal hardware or pacemakers, or weight exceeding DXA table limit (>350 lb). All individual testing was completed within a 2‐h period. Fat packets were prepared using lard wrapped in plastic and applied exogenously in defined locations. Each participant completed body composition measurements with ADP and DXA (both testing modalities completed with and without 1 kg of exogenously applied FM). Both DXA and ADP were highly accurate in detecting an overall increase in body mass associated with exogenously applied 1 kg of FM (0.99 kg vs. 0.97 kg, respectively). DXA more accurately detected exogenous fat increase as FM compared to ADP (0.93 kg; 90% CI for the mean of the difference: 0.83 to 1.03 kg vs. 0.45 kg; 90% CI: 0.19 to 0.71 kg, respectively). The accuracy of body mass detection was similar for males and females (0.97 vs. 1.02 for DXA and 0.92 vs. 1.02 for ADP, respectively), though accuracy in detecting added mass as fat was less accurate in males than females (0.84 vs. 1.00 for DXA and 0.39 vs. 0.51 for ADP, respectively). Both DXA and ADP are accurate in detecting an overall increase in body mass associated with exogenously applied 1 kg of FM. However, DXA is more accurate than ADP in correctly identifying the increase in body mass as FM, as opposed to fat‐free mass.