Seroepidemiología de la enfermedad de Chagas en México
Seroepidemiología de la enfermedad de Chagas en México
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墨西哥恰加斯病血清流行病学
DOI：
10.1590/s0102-311x200200060002400028
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发表时间：
1992
影响因子：
2.3
通讯作者：
J. Sepúlveda
中科院分区：
文献类型：
--
作者：
O. Velasco;J. L. Valdespino;R. Tapia;Benito Salvatierra;C. Guzmán;C. Magos;A. Llausas;G. Gutiérrez;J. Sepúlveda
墨西哥缺乏关于恰加斯病的信息，以及关于其重要性的争议，是国家血清流行病学调查（NSS）中克氏锥虫血清阳性率研究的基础。这一信息代表了疾病流行率和与国家健康有关的其他因素方面的全国情况。不幸的是，NSS不是一个很好的美洲锥虫研究的信息来源，因为它在分散的农村地区的覆盖率很低。然而，国家抽样调查的结果表明，恰加斯病在墨西哥的分布不规则，评价中使用的不同稀释水平的血清阳性率为1.6、0.5和0.2。调查数据显示，恰加斯病的重要性低于其他作者所提到的。国家抽样调查局的数据证实了已经报告的疾病传播地区，并在伊达尔戈、恰帕斯和韦拉克鲁斯发现了一些新的疾病传播地区。调查还发现，在下加利福尼亚边境城市，移徙工人体内有查加斯抗体，这种情况表明，在该国被认为没有这种疾病的地区，存在输血的风险。四分之三（74.5%）的血清反应阳性人群年龄小于39岁。此外，四岁以下儿童被感染的事实表明，自然传播在某些地区仍然非常重要。虽然在社会经济地位较低的群体中血清阳性率较高，但一些社会经济地位较高的人也受到影响。造成这种情况的原因可能是这些人中有许多人在热带地区拥有度假屋。
The lack of information about Chagas disease in Mexico, as well as the controversy concerning its importance, was the basis for the seroprevalence study of Trypanosoma cruzi in the National Seroepidemiology Survey (NSS). This information was representative of the national situation with regard to disease prevalences and other factors related to the nation's health. Unfortunately the NSS was not a very good information source for the study of trypanosomiasis americana, because its coverage in the disperse rural areas was poor. Nevertheless, the results of the NSS indicated that Chagas disease has an irregular distribution in Mexico with seroprevalences of 1.6, 0.5 and 0.2 for the different dilution levels used in the evaluation. The survey data showed Chagas disease to be less important than that mentioned by other authors. The NSS data confirmed the areas of disease transmission already reported and identified some new ones in Hidalgo, Chiapas and Veracruz. The survey also detected migratory workers with Chagas antibodies in Baja California border cities, a situation which indicates a risk for blood transfusion in areas of the country presumed to be free of the disease. Three quarters (74.5%) of the seropositive population were less than 39 years old. Moreover, the fact that children of less than four year were infected suggests that natural transmission is still very important in some areas. Although the seroprevalences were greater in the lower socio-economic groups, some persons of the higher socio-economic level were also affected. This situation may be explained by the fact that many of these persons own vacation homes in tropical areas.