Canine visceral leishmaniasis, United States and Canada, 2000-2003
Canine visceral leishmaniasis, United States and Canada, 2000-2003
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DOI：
10.3201/eid1203.050811
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发表时间：
2006-03-01
影响因子：
11.8
通讯作者：
Schantz, PM
中科院分区：
文献类型：
--
作者：
Duprey, ZH;Steurer, FJ;Schantz, PM
内脏利什曼病由杜氏利什曼原虫复合体原虫引起，是一种通过媒介传播的人、狗和其他哺乳动物感染。2000年，这种感染被认为是导致纽约一家狗舍里的猎狐犬高发病率和死亡率的原因。对35个州和加拿大4个省的12000只猎狐犬和其他犬类以及185人进行了血清调查，以确定猎狐犬、其他犬类和野犬中的地理范围、流行率、宿主范围和传播方式，并评估人类可能的感染情况。猎狐犬感染利什曼原虫。在18个州和加拿大2个省发现了这种病毒。没有在人类身上发现感染的证据。在北美，这种感染似乎在猎狐犬中广泛存在，并仅限于堵塞到狗的传播机制；然而，如果这种生物体适应了本土血吸虫的媒介传播，人类接触的可能性将大大增加。
Visceral leishmaniasis, caused by protozoa of the genus Leishmania donovani complex, is a vectorborne zoonotic infection that infects humans, dogs, and other mammals. In 2000, this infection was implicated as causing high rates of illness and death among foxhounds in a kennel,in New York. A serosurvey of > 12,000 foxhounds and other canids and 185 persons in 35 states and 4 Canadian provinces was performed to determine geographic extent, prevalence, host range, and modes of transmission within foxhounds, other dogs, and wild canids and to assess possible infections in humans. Foxhounds infected with Leishmania spp. were found in 18 states and 2 Canadian provinces. No evidence of infection was found in humans. The infection in North America appears to be widespread in foxhounds and limited to clog-to-dog mechanisms of transmission; however, if the organism becomes adapted for vector transmission by indigenous phlebotomines, the probability of human exposure will be greatly increased.