Do automated text messages increase adherence to acne therapy? Results of a randomized, controlled trial
Do automated text messages increase adherence to acne therapy? Results of a randomized, controlled trial
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DOI：
10.1016/j.jaad.2012.02.031
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发表时间：
2012-12-01
影响因子：
13.8
通讯作者：
Jacobe, Heidi
中科院分区：
文献类型：
--
作者：
Boker, Andreas;Feetham, H. Jill;Jacobe, Heidi
背景：痤疮是一种常见的皮肤病，通常需要复杂的治疗方案。患者不遵守规定的药物治疗方案是治疗failure.Objective的一个因素：本研究的目的是确定是否每天自动短信将导致增加遵守推荐使用的局部痤疮药物，从而更大的改善痤疮。40例轻度至中度痤疮患者，上午服用克林霉素/过氧苯甲酰1%/5%凝胶，晚上服用阿达帕林0.3%凝胶，持续12周。每个给药管均配有电子给药事件监测系统帽（MEMS，Aardex Group，锡永，瑞士）（以记录每次打开/关闭给药管的日期和时间）。20名患者被随机分配接受定制的每天两次的短信，指导他们应用他们的早晨和晚上的药物。其余的患者（N = 20），谁没有收到短信，作为对照subjects.Results：平均坚持率为每天正确应用两种药物超过12周的提醒组和对照组的患者分别为33.9%和36.5%（P = 0.75）。两组患者有类似的临床改善他们的acneum.Limitations：小样本量可能会限制检测研究groups.Conclusions之间的差异的能力：电子提醒的形式，每天，定制的短信与轻度至中度痤疮患者的局部用药依从性的显着差异，并没有显着的治疗反应的影响。（J Am Acad Dermatol 2012;67：1136-42.）
Background: Acne is a common skin condition often requiring complex therapeutic regimens. Patient nonadherence to prescribed medication regimens is a factor in treatment failure.Objective: The goal of this study was to determine if daily automated text messages would result in increased adherence to recommended use of topical acne medication and consequently greater improvement in acne.Methods: Forty patients with mild to moderate acne were prescribed clindamycin/benzoyl peroxide 1%/5% gel in the mornings and adapalene 0.3% gel in the evenings for 12 weeks. Each medication tube was fitted with an electronic Medication Event Monitoring System cap (MEMS, Aardex Group, Sion, Switzerland) (to record the date and time of every opening/closing of the tube). Twenty patients were randomly assigned to receive customized twice-daily text messages instructing them to apply their morning and evening medication. The remainder of patients (N = 20), who did not receive text messages, served as control subjects.Results: Mean adherence rates for the correct application of both medications on a daily basis over 12 weeks was 33.9% for patients in the reminder group and 36.5% for patients in the control group (P = .75). Patients in both groups had similar clinical improvement of their acne.Limitations: The small sample size may limit the ability to detect differences between the study groups.Conclusions: Electronic reminders in the form of daily, customized text messages were not associated with significant differences in adherence to topical medications in patients with mild to moderate acne and had no significant effect on therapeutic response. (J Am Acad Dermatol 2012;67:1136-42.)