Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant.
Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant.
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DOI：
10.3201/eid2105.141927
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发表时间：
2015-05
影响因子：
11.8
通讯作者：
de Haan CA
中科院分区：
文献类型：
--
作者：
de Vries E;Guo H;Dai M;Rottier PJ;van Kuppeveld FJ;de Haan CA
2014年，新型高致病性禽流感A型H5N2、H5N5、H5N6和H5N8病毒在亚洲、欧洲和北美爆发。这些病毒的H5基因形成了一个单系群，从进化枝2.3.4 H5N1变异体进化而来。这种新的H5Nx组合的迅速出现在H5N1进化史上是前所未有的。
In 2014, novel highly pathogenic avian influenza A H5N2, H5N5, H5N6, and H5N8 viruses caused outbreaks in Asia, Europe, and North America. The H5 genes of these viruses form a monophyletic group that evolved from a clade 2.3.4 H5N1 variant. This rapid emergence of new H5Nx combinations is unprecedented in the H5N1 evolutionary history.