In vivo evaluation of human skin anisotropy by polarization-sensitive optical coherence tomography.
In vivo evaluation of human skin anisotropy by polarization-sensitive optical coherence tomography.
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DOI：
10.1364/boe.2.002623
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发表时间：
2011-09-01
影响因子：
3.4
通讯作者：
Yasuno Y
中科院分区：
文献类型：
--
作者：
Sakai S;Yamanari M;Lim Y;Nakagawa N;Yasuno Y
我们使用偏振敏感光学相干断层扫描（PS-OCT）对机械变形的人体皮肤双折射的各向异性变化进行了体内三维分析。前额乳头-真皮双折射率在皮肤与体轴平行收缩时显著增加，在皮肤与体轴垂直收缩时显著降低。乳头-真皮双折射的正面图像显示个体受试者之间存在差异，平行于身体轴线的收缩和垂直于身体轴线的拉伸都促进了宏观绳状双折射域的形成。我们发现PS-OCT对于了解皮肤中胶原结构的各向异性特性是有用的。
We performed an in vivo three-dimensional analysis of anisotropic changes in the dermal birefringence of mechanically deformed human skin using polarization-sensitive optical coherence tomography (PS-OCT). The papillary-dermal birefringence of the forehead increased significantly when the skin was shrunk parallel to the body axis, and decreased significantly when the skin was shrunk perpendicular to the body axis. En-face images of the papillary-dermal birefringence revealed variations among individual subjects, and that both shrinking parallel to and stretching in perpendicular to the body axis promoted the formation of macro rope-like birefringent domains. We found that PS-OCT is useful for understanding anisotropic properties of collagen structure in the skin.