Age of onset of social anxiety disorder in depressed outpatients
Age of onset of social anxiety disorder in depressed outpatients
复制标题
DOI：
10.1016/j.janxdis.2010.08.012
复制
发表时间：
2011-01-01
影响因子：
10.3
通讯作者：
Zimmerman, Mark
中科院分区：
文献类型：
--
作者：
Dalrymple, Kristy L.;Zimmerman, Mark
在这种共病模式的患者中，社交焦虑症(SAD)的发病通常先于严重抑郁障碍(MDD)。本研究基于半结构化诊断性访谈，对412例确诊为MDD和SAD的精神科门诊患者的临床特征与三组SAD发病人群(儿童期、青春期、成年期)之间的关系进行了研究。与成年起病组相比，儿童和青少年SAD发作组更有可能在18岁之前报告MDD起病，并至少有过一次自杀企图。与成年起病组相比，儿童期SAD发作组也更有可能患有慢性MDD，既往社会功能较差，MOD发病风险增加。研究结果表明，在童年或青春期起病的SAD患者可能特别有可能患上更严重和更慢性的抑郁症。(C)2010爱思唯尔有限公司。保留所有权利。
Onset of social anxiety disorder (SAD) often precedes that of major depressive disorder (MDD) in patients with this comorbidity pattern. The current study examined the association between three SAD onset groups (childhood, adolescent, adulthood) and clinical characteristics of 412 psychiatric outpatients diagnosed with MDD and SAD based on a semi-structured diagnostic interview. Childhood and adolescent SAD onset groups were more likely to report an onset of MDD prior to age 18 and have made at least one prior suicide attempt compared to the adulthood onset group. The childhood SAD onset group also was more likely to have chronic MDD, poorer past social functioning, and an increased hazard of MOD onset compared to the adulthood onset group. Findings suggest that patients with an onset of SAD in childhood or adolescence may be particularly at risk for a more severe and chronic course of depressive illness. (C) 2010 Elsevier Ltd. All rights reserved.