PRESERVATION OF THE CANINE LIVER FOR 24-48 HOURS USING SIMPLE COLD-STORAGE WITH UW SOLUTION

PRESERVATION OF THE CANINE LIVER FOR 24-48 HOURS USING SIMPLE COLD-STORAGE WITH UW SOLUTION
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DOI:
10.1097/00007890-198810000-00010
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发表时间:
1988-10-01
期刊:
影响因子:
6.2
通讯作者:
BELZER, FO
BELZER, FO
中科院分区:
医学2区
文献类型:
--
作者:
JAMIESON, NV;SUNDBERG, R;BELZER, FO

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描述了一系列 29 例狗原位肝移植的结果。将肝脏保存在新的冷藏液UW溶液中,并在保存24、30、36和48小时后成功移植。 24小时后移植的所有六只动物均在移植后存活超过5天,并且具有良好的移植功能。冷藏 30 小时后,六只中的四只存活了至少 5 天,冷藏 36 小时后,五只中的五只存活了至少 5 天。连续六只接受冷藏 48 小时移植的狗中,有五只存活了 5 天或更长时间。该解决方案比所有现有的肝脏保存冷藏解决方案取得了重大进步。
The results of a series of 29 orthotopic liver transplants in the dog are described. The livers were preserved in a new cold storage fluid, UW solution, and were successfully transplanted after periods of storage of 24, 30, 36, and 48 hr. All six animals transplanted after 24 hr survived beyond 5 days after transplantation and had excellent graft function. Four of six survived for at least 5 days after 30 hr of cold storage, and five of five after 36 hr. Five of six consecutive dogs that received transplants that had been cold-stored for 48 hr survived for 5 or more days. This solution represents a substantial advance over all existing cold storage solutions for liver preservation.