Whole-genome characterization of embryonic stage inbreeding depression in a selfed loblolly pine family.

Whole-genome characterization of embryonic stage inbreeding depression in a selfed loblolly pine family.
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自交火炬松家族胚胎期近交衰退的全基因组特征。

DOI:
10.1093/genetics/155.1.337
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发表时间:
2000
期刊:
影响因子:
3.3
通讯作者:
O'Malley,DM
O'Malley,DM
中科院分区:
生物学2区
文献类型:
--
作者:
Remington,DL;O'Malley,DM

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近交抑制在植物种群和交配系统的进化中很重要。先前的研究表明,植物中早期作用的近交抑制主要是由于致死等位基因和可能的上位相互作用所致。分子标记的最新进展使遗传图谱成为研究近亲繁殖抑郁症遗传结构的有力工具。我们使用来自基本完整的基因组图谱的 AFLP 标记数据,描述了火炬松 (Pinus taedaL.) 自交家族胚胎活力位点的全基因组评估。使用最大似然区间作图程序根据分离率估计基因座位置和效应。我们鉴定了 19 个位点,这些位点显示出中度有害至致命的胚胎效应。这些位点占 >13 个致死当量,高于报道的火炬松 8.5 个致死当量的平均值。活力等位基因主要表现出隐性作用,尽管潜在的超显性发生在 3 个基因座上。我们在成对标记相关性的分布或与有害等位基因相关的标记数量的适应性回归中没有发现上位性的证据。半致死等位基因在胚胎近交衰退中的主导作用对于孤立种群的进化以及针叶树的遗传保护和育种计划具有影响。
Inbreeding depression is important in the evolution of plant populations and mating systems. Previous studies have suggested that early-acting inbreeding depression in plants is primarily due to lethal alleles and possibly epistatic interactions. Recent advances in molecular markers now make genetic mapping a powerful tool to study the genetic architecture of inbreeding depression. We describe a genome-wide evaluation of embryonic viability loci in a selfed family of loblolly pine (Pinus taedaL.), using data from AFLP markers from an essentially complete genome map. Locus positions and effects were estimated from segregation ratios using a maximum-likelihood interval mapping procedure. We identified 19 loci showing moderately deleterious to lethal embryonic effects. These loci account for >13 lethal equivalents, greater than the average of 8.5 lethal equivalents reported for loblolly pine. Viability alleles show predominantly recessive action, although potential overdominance occurs at 3 loci. We found no evidence for epistasis in the distribution of pairwise marker correlations or in the regression of fitness on the number of markers linked to deleterious alleles. The predominant role of semilethal alleles in embryonic inbreeding depression has implications for the evolution of isolated populations and for genetic conservation and breeding programs in conifers.
沿海花旗松 Pseudotsuga menziesii var. 的胚胎遗传负荷。
DOI: 10.1086/282609
发表时间: 1969
期刊: The American Naturalist
影响因子: --
作者:
F. Sorensen
通讯作者: F. Sorensen
DOI: 10.1139/x83-151
发表时间: 1983-01-01
影响因子: 2.2
作者:
FOWLER, DP;PARK, YS
通讯作者: PARK, YS
DOI: 10.1111/j.1558-5646.1993.tb01240.x
发表时间: 1993
期刊: Evolution
影响因子: 3.3
作者:
J. Willis
通讯作者: J. Willis
林木种群中致命等位基因的频率
DOI: 10.1111/j.1558-5646.1987.tb05882.x
发表时间: 1987
期刊: Evolution
影响因子: 3.3
作者:
G. Namkoong;J. Bishir
通讯作者: J. Bishir
DOI: 10.1017/s0016672300029256
发表时间: 1991-04-01
期刊: GENETICAL RESEARCH
影响因子: --
作者:
CHARLESWORTH, B;MORGAN, MT;CHARLESWORTH, D
通讯作者: CHARLESWORTH, D