New antifeedant bromopyrrole alkaloid from the Caribbean sponge Stylissa caribica
New antifeedant bromopyrrole alkaloid from the Caribbean sponge Stylissa caribica
复制标题
DOI：
10.1021/np000482s
复制
发表时间：
2001-10-01
影响因子：
5.1
通讯作者：
Köck, M
中科院分区：
文献类型：
--
作者：
Assmann, M;van Soest, RWM;Köck, M
在这份关于海绵 Stylissa caribica 化学的第一份报告中，分离并鉴定了两种已知的溴吡咯代谢物和一种新化合物 N-甲基二溴异法克林 (1)。 1的结构是使用光谱方法和计算机程序COCON确定的。 N-甲基二溴异磷花蛋白 (1) 被证明是 Stylissa caribica 中唯一的次生代谢物，其天然浓度可有效抑制常见杂食性珊瑚鱼的摄食。
In this first report on the chemistry of the sponge Stylissa caribica, two known bromopyrrole metabolites and a new compound, N-methyldibromoisophakellin (1), were isolated and identified. The structure of 1 was determined using spectroscopic methods and the computer program COCON. N-Methyldibromoisophakellin (1) was shown to be the only secondary metabolite in Stylissa caribica that, at its natural concentration, is active as a feeding deterrent against a common omnivorous reef fish.