Trends in the prevalence of heart diseases over a ten-year period from single-center observations based on a large echocardiographic database
Trends in the prevalence of heart diseases over a ten-year period from single-center observations based on a large echocardiographic database
复制标题
DOI：
10.1631/jzus.b1500136
复制
发表时间：
2016-01-01
影响因子：
5.1
通讯作者：
Ge, Jun-bo
中科院分区：
文献类型：
--
作者：
Lu, Hao;Pan, Wen-zhi;Ge, Jun-bo
近年来，中国心脏病发病率趋势的数据很少。我们利用我们中心的一个大型超声心动图数据库，分析了2003年12月以来几种常见心脏病的患病率趋势。本研究回顾性分析了我科2003年至2012年的超声心动图数据库。研究共纳入385682例病例。风湿性心脏病的患病率在10年间有所下降，从2003年的4.04%降至2012年的3.06%（P < 0.01）。感染性心内膜炎的平均患病率也从2003年7月的0.37%下降到2008年12月的0.27%（P < 0.001）。肥厚型心肌病的患病率约为1.8%，其中心尖肥厚型心肌病占20%，肥厚型梗阻性心肌病占20%。从2003年7月到2008年12月，三种最常见的成人先天性心脏病（CHD）的患病率下降了约10%（均P < 0.001）。中度肺动脉高压（PAH）或左室收缩功能不全（LVSD）的患病率在10年期间下降（P < 0.001），但重度PAH或LVSD的患病率无变化（P > 0.05）。本研究间接表明，近年来中国几种常见心脏病的患病率有所下降。
There is a paucity of data regarding trends in the incidence of heart disease in China during recent years. Using a large echocardiography database in our center, we analyzed trends in the prevalence of several common heart diseases from Dec. 2003. This study retrospectively analyzed the echocardiographic database in our Department from 2003 to 2012. A total of 385 682 cases were included in the study. The prevalence of rheumatic heart disease decreased over the 10-year period, from 4.04% in 2003 to 3.06% in 2012 (P < 0.01). Infective endocarditis also decreased, from a mean prevalence of 0.37% in July 2003 to 0.27% in Dec. 2008 (P < 0.001). The prevalence of hypertrophic cardiomyopathy, which includes 20% apical hypertrophic cardiomyopathy and 20% hypertrophic obstructive cardiomyopathy, was about 1.8%. The prevalence of the three most common adult congenital heart diseases (CHDs) decreased by about 10% from July 2003 to Dec. 2008 (all P < 0.001). The prevalence of moderate pulmonary arterial hypertension (PAH) or left ventricular systolic dysfunction (LVSD) decreased during the 10-year period (P < 0.001), but there was no change in the prevalence of severe PAH or LVSD (P > 0.05). The present study indirectly demonstrates that the prevalence of several common heart diseases in China has declined in recent years.