A silk purse from a sow's ear-bioinspired materials based on a-helical coiled coils.
A silk purse from a sow's ear-bioinspired materials based on a-helical coiled coils.
复制标题
一款丝绸钱包，采用母猪耳朵仿生材料制成，基于非螺旋线圈。
DOI：
10.1016/j.ceb.2014.12.010
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发表时间：
2015
影响因子：
7.5
通讯作者：
Quinlan RA
中科院分区：
文献类型：
--
作者：
Quinlan RA
从羊毛α-角蛋白到作为疫苗平台的紧急卷曲螺旋技术。药物输送和未来的纳米复合材料。包装，编织和储存α-螺旋卷曲螺旋纤维。设计和提供卷曲螺旋几何形状的结构工具。过去几年预示着中间纤维的非凡时代，其结构特性的新发现包括第一个晶体学-基于波形蛋白的模型，建立在化学交联确定的丝内相互作用的实验数据上。现在，随着这些和其他进展，他们的组装，他们的生物力学和细胞生物学特性概述在这篇评论中，开发的生物力学和结构特性的中间丝，其纳米复合材料和仿生衍生物在生物医学和私营部门已经开始。
HighlightsFrom wool α-keratins to emergent coiled coil technologies as vaccine platforms.Drug delivery and future nanocomposites.Packing, weaving and storing α-helical coiled coil fibres.Structural tools to design and deliver coiled coil geometries.This past few years have heralded remarkable times for intermediate filaments with new revelations of their structural properties that has included the first crystallographic-based model of vimentin to build on the experimental data of intra-filament interactions determined by chemical cross-linking. Now with these and other advances on their assembly, their biomechanical and their cell biological properties outlined in this review, the exploitation of the biomechanical and structural properties of intermediate filaments, their nanocomposites and biomimetic derivatives in the biomedical and private sectors has started.