PET imaging of bacterial infections with fluorine-18-labeled maltohexaose.
PET imaging of bacterial infections with fluorine-18-labeled maltohexaose.
复制标题
用氟-18标记的麦芽糖类对细菌感染的PET成像。
DOI:
10.1002/anie.201408533
复制
发表时间:
2014-12-15
影响因子:
16.6
通讯作者:
Murthy, Niren
中科院分区:
文献类型:
--
作者:
Ning, Xinghai;Seo, Wonewoo;Lee, Seungjun;Takemiya, Kiyoko;Rafi, Mohammad;Feng, Xuli;Weiss, Daiana;Wang, Xiaojian;Williams, Larry;Camp, Vernon M.;Eugene, Malveaux;Taylor, W. Robert;Goodman, Mark;Murthy, Niren
关键词:
A new positron emission tomography (PET) tracer, composed of 18F labeled maltohexaose (MH18F), can image bacteria in vivo with a sensitivity and specificity that is orders of magnitude better than fluorodeoxyglucose (18FDG). MH18F can detect early stage infections composed of as few as 105 E.coli colony forming units (CFUs), and can identify drug resistance in bacteria in vivo. MH18F has the potential to improve the diagnosis of bacterial infections given its unique combination of high specificity and sensitivity for bacteria.
登录
查看更多内容
影响因子:
3.2
作者:
Dippel, R;Boos, W
通讯作者:
Boos, W
影响因子:
3.1
作者:
Kim, DW;Choe, YS;Chi, DY
通讯作者:
Chi, DY
DOI:
10.1007/s00259-004-1646-2
发表时间:
2005-02-01
影响因子:
9.1
作者:
Langer, O;Brunner, M;Müller, M
通讯作者:
Müller, M
影响因子:
2.6
作者:
Klebba, PE
通讯作者:
Klebba, PE
影响因子:
9.3
作者:
Bhattacharya, Anish;Kochhar, Rakesh;Mittal, Bhagwant R.
通讯作者:
Mittal, Bhagwant R.