Cardiac MRI in pulmonary artery hypertension: correlations between morphological and functional parameters and invasive measurements
Cardiac MRI in pulmonary artery hypertension: correlations between morphological and functional parameters and invasive measurements
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DOI：
10.1007/s00330-009-1664-3
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发表时间：
2010-05-01
影响因子：
5.9
通讯作者：
Chabbert, Valerie
中科院分区：
文献类型：
--
作者：
Alunni, Jean-Philippe;Degano, Bruno;Chabbert, Valerie
比较肺动脉高压（PH）患者的心脏MRI与右心导管检查，并评估其评估PH严重程度的能力。纳入40例患者。MRI包括电影和相位对比序列，心室功能，心脏腔面积和比例，室间隔（IVS）在收缩和舒张时的位置，以及血流测量。我们根据PH的严重程度分为四组，根据IVS位置分为三组：A，正常位置；B，舒张期异常；C，舒张、收缩期异常。IVS位置与肺动脉压和肺血管阻力相关。与位置正常的患者相比，间隔位置异常的患者肺动脉中位压和阻力明显升高。右心室射血分数与PVR、右心室收缩末容积与PAP、右心室面积变化百分比与PVR、舒张室与收缩室面积比与PVR均有较好的相关性。这些参数与PH严重程度显著相关。心脏MRI可以帮助评估PH的严重程度。
To compare cardiac MRI with right heart catheterisation in patients with pulmonary hypertension (PH) and to evaluate its ability to assess PH severity.Forty patients were included. MRI included cine and phase-contrast sequences, study of ventricular function, cardiac cavity areas and ratios, position of the interventricular septum (IVS) in systole and diastole, and flow measurements. We defined four groups according to the severity of PH and three groups according to IVS position: A, normal position; B, abnormal in diastole; C, abnormal in diastole and systole.IVS position was correlated with pulmonary artery pressures and PVR (pulmonary vascular resistance). Median pulmonary artery pressures and resistance were significantly higher in patients with an abnormal septal position compared with those with a normal position. Correlations were good between the right ventricular ejection fraction and PVR, right ventricular end-systolic volume and PAP, percentage of right ventricular area change and PVR, and diastolic and systolic ventricular area ratio and PVR. These parameters were significantly associated with PH severity.Cardiac MRI can help to assess the severity of PH.