Sex hormone changes in morbidly obese patients after vertical banded gastroplasty
Sex hormone changes in morbidly obese patients after vertical banded gastroplasty
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DOI：
10.1159/000008556
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发表时间：
1998-01-01
影响因子：
1.6
通讯作者：
Alexiou, D
中科院分区：
文献类型：
--
作者：
Bastounis, EA;Karayiannakis, AJ;Alexiou, D
在 57 名病态肥胖患者（19 名男性和 38 名绝经前女性）术前和垂直带状胃成形术后 12 个月测量了血清性激素水平。在男性组中，雌二醇显着减少，卵泡刺激素（FSH）、总睾酮和性激素结合球蛋白（SHBG）增加。在女性患者中，雌二醇、总睾酮和游离睾酮显着下降，FSH 和 SHBG 增加。 5 名女性术前出现的月经不调在成功减肥后得到了纠正。总之，与病态肥胖相关的性激素水平改变和妇科异常可以通过垂直带状胃成形术后适当的体重减轻来纠正。
Serum sex hormone levels were measured preoperatively in 57 morbidly obese patients (19 men and 38 premenopausal women) and 12 months after vertical banded gastroplasty. In the male group, there was a significant decrease in estradiol and an increase in follicle-stimulating hormone (FSH), total testosterone and sex-hormone-binding globulin (SHBG). Among female patients, a significant decrease in estradiol, total and free testosterone and an increase in FSH and SHBG was found. Irregular menses present preoperatively in 5 women were corrected after successful weight loss. In conclusion, altered sex hormonal levels and gynecologic abnormalities associated with morbid obesity are corrected with adequate weight loss following vertical banded gastroplasty.