Designing translationally relevant preclinical studies of new therapeutics.
Designing translationally relevant preclinical studies of new therapeutics.
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设计新疗法的转化相关临床前研究。
DOI：
10.1113/ep086296
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发表时间：
2017
影响因子：
2.7
通讯作者：
Wells DJ
中科院分区：
文献类型：
--
作者：
Wells DJ
这篇文章的重点是使用长期的饮食槲皮素富集在小鼠模型的神经肌肉疾病。讨论的主题包括需要终身治疗来治疗遗传性疾病的动物模型，12个月的槲皮素膳食补充剂的效果，以及与未治疗的mdx小鼠相比，治疗小鼠的促肾上腺素活性增加。
The article focuses on the uses of long-term dietary quercetin enrichment in a mouse model of a neuromuscular disease. Topics discussed include need of life-long therapy to treat the animal model that have inherited diseases, effects of 12 months of dietary supplement of quercetin, and increased locomoter activity in the treated mice as compared with the untreated mdx mice.