Early determinants of development: a lipid perspective
Early determinants of development: a lipid perspective
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DOI：
10.3945/ajcn.2009.27113g
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发表时间：
2009-05-01
影响因子：
7.1
通讯作者：
Carlson, Susan E.
中科院分区：
文献类型：
--
作者：
Carlson, Susan E.
本文源自国际生命科学研究所关于健康和发育的早期营养决定因素的研讨会。关于脂质的介绍主要集中于必需脂肪酸的长链产物，特别是二十二碳六烯酸 (22:6n-3)，以及认知发展，分别是早期人类营养中研究最多的脂质和结果。由于最近有几篇关于该主题的评论，因此本评论对早期发育和脂质采取了更广泛的视角：根据一些人类研究和动物研究的观察结果，扩大研究议程是合理的。已知通过母乳以不同量向婴儿提供的其他脂质是胆固醇和神经节苷脂。简短的部分讨论了当前的知识状况和一些可以探讨的问题。美国临床营养杂志 2009； 89（补充）：1523S-9S。
This article results from an International Life Sciences Institute workshop on early nutritional determinants of health and development. The presentation on lipids focused mainly on the longer-chain products of the essential fatty acids, particularly docosahexaenoic acid (22:6n-3), and cognitive development as among the most studied lipids and outcomes, respectively, in early human nutrition. Because there have been several recent reviews on this topic, the present review takes a broader perspective with respect to both early development and lipids: an expanded research agenda is plausible on the basis of observations from some human studies and from animal studies. Other lipids known to be provided in variable amounts to infants through human milk are cholesterol and gangliosides. Short sections address the current state of knowledge and some questions that could be pursued. Am J Clin Nutr 2009; 89(suppl): 1523S-9S.