Development of a pulsatile flow-generating circulatory-assist device
Development of a pulsatile flow-generating circulatory-assist device
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脉动流发生循环辅助装置的研制
DOI：
10.1007/s10047-010-0493-0
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发表时间：
2010
影响因子：
1.3
通讯作者：
N. Yahagi
中科院分区：
文献类型：
--
作者：
Syuji Inamori;Yutaka Fujii;Tomoya Oshita;Yutaka Kobayashi;M. Minamiyama;Sinobu Sasaki;Takashi Murakami;I. Sakuma;Masataka Gunshin;Y. Suematsu;N. Yahagi
我们开发了一种新的循环辅助装置，可以产生与患者舒张期同步的脉动辅助流量。该装置由引流管、离心泵、氧合器和输送管组成。一个便携式电磁阀装置组成的脉冲发生器和夯实机，产生间歇性的机械压缩，是连接到枕头的发送管。进行了初步的动物实验。在初步48小时试验运行期间，未观察到动物血流动力学变化或任何器械问题。证实了显著的舒张增强。这种新设备可能有助于治疗严重心力衰竭患者，并且可能比单独使用经皮心肺支持（PCPS）更有用。
We developed a new circulation-assist device that can generate pulsatile assist flow synchronized with the patient’s diastolic phase. The device is composed of a drainage tube, a centrifugal pump, an oxygenator, and a sending tube. A portable magnetic valve device composed of a pulse generator and a tamper, which produces intermittent mechanical compression, is attached to the pillow of the sending tube. Preliminary animal experiments were conducted. No changes in the animals’ hemodynamics or any device problems were observed during a preliminary 48-h test run. Significant diastolic augmentation was confirmed. This new device may be useful in treating patients with severe heart failure and could be more useful than using percutaneous cardiopulmonary support (PCPS) alone.