Distribution of Neuropeptide-Like Immunoreactive Nerve Fibers in the Canine Larynx

Distribution of Neuropeptide-Like Immunoreactive Nerve Fibers in the Canine Larynx
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犬喉中神经肽样免疫反应性神经纤维的分布

DOI:
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发表时间:
1990
期刊:
Otolaryngology Head & Neck Surgery
影响因子:
--
通讯作者:
S. Masuko
S. Masuko
中科院分区:
--
文献类型:
--
作者:
Michiru Kawasoe;T. Shin;S. Masuko

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本文观察了犬喉内神经肽免疫反应阳性神经纤维的分布。在声门下和声上区的上皮中,观察到P物质(SP)和降钙素基因相关多肽(CGRP)免疫反应(IR)神经纤维的密集分布。声门下区可见血管活性肠肽(VIP)阳性的上皮内神经纤维。在喉腺中,VIP-IR神经纤维密集分布,少数SP-和ENK-IR神经纤维分布在腺泡周围。在固有层的动脉壁中,可见许多VIP-、SP-和CGRP-IR神经纤维,而神经肽Y-、ENK-和VIP-IR神经纤维主要分布在发声肌的动脉周围。在声带游离缘,上皮内和固有层动脉周围的免疫反应阳性神经纤维很少。这些结果表明,有区域差异的发生肽神经纤维支配的上皮和血管在喉和上皮的感知机制和调节系统的局部血流是不同的,根据其位置在喉。
The distribution of neuropeptide immunoreactive nerve fibers in the canine larynx was examined. In the epithelium of supra- and subglottic regions, a dense distribution of substance P (SP)- and calcitonin gene-related polypeptide (CGRP)-immunoreactive (IR) nerve fibers was observed. Some vasoactive intestinal polypeptide (VIP)-IR intraepithelial nerve fibers were also seen in the subglottic region. In the laryngeal glands, a dense distribution of VIP-IR nerve fibers with a few SP- and enkephalin (ENK)-IR nerve fibers were found around the acini. In the walls of arteries in the lamina propria, many VIP-, SP-, and CGRP-IR nerve fibers were seen, whereas neuropeptide Y-, ENK-, and VIP-IR nerve fibers were predominantly distributed around the arteries in the vocal muscle. In the free edge of the vocal cord, few immunoreactive nerve fibers were detected within the epithelium and around the arteries in the lamina propria. These results suggest that there are regional differences in the occurrence of peptides in nerve fibers innervating the epithelium and the blood vessels in the larynx and that the perception mechanism of the epithelium and the regulatory system of local blood flow are varied according to their location in the larynx.
甲硫氨酸脑啡肽调节外周肾上腺素能神经传递。
DOI: --
发表时间: 1982
期刊: The Journal of pharmacology and experimental therapeutics
影响因子: --
作者:
Gaddis,RR;Dixon,WR
通讯作者: Dixon,WR