Medical Management of Chronic Pancreatitis in Children: A Position Paper by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Pancreas Committee.
Medical Management of Chronic Pancreatitis in Children: A Position Paper by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Pancreas Committee.
复制标题
DOI：
10.1097/mpg.0000000000003001
复制
发表时间：
2021-02-01
影响因子：
2.9
通讯作者：
Abu-El-Haija M
中科院分区：
文献类型：
--
作者：
Freeman AJ;Maqbool A;Bellin MD;Goldschneider KR;Grover AS;Hartzell C;Piester TL;Szabo F;Kiernan BD;Khalaf R;Kumar R;Rios M;Husain SZ;Morinville VD;Abu-El-Haija M
本立场文件根据现有医学文献总结了目前对儿童慢性胰腺炎 (CP) 医疗治疗的理解，并结合了对营养、疼痛、生活方式考虑和 CP 后遗症的最新进展。本文是对儿童脑瘫内窥镜和手术方面的平行立场文件的补充和整合。还回顾了与胰酶替代疗法 (PERT)、抗氧化剂的使用和其他 CP 医学疗法相关的概念和争议。亮点包括纳入 PERT、CP 相关糖尿病和多模式疼痛管理（包括镇痛梯）的医疗决策工具。还回顾了我们对儿童脑瘫理解的差距以及进一步研究的途径。
This position paper summarizes the current understanding of the medical management of chronic pancreatitis (CP) in children in light of the existing medical literature, incorporating recent advances in understanding of nutrition, pain, lifestyle considerations, and sequelae of CP. This article complements and is intended to integrate with parallel position papers on endoscopic and surgical aspects of CP in children. Concepts and controversies related to pancreatic enzyme replacement therapy (PERT), the use of antioxidants and other CP medical therapies are also reviewed. Highlights include inclusion of tools for medical decision-making for PERT, CP-related diabetes, and multimodal pain management (including an analgesia ladder). Gaps in our understanding of CP in children and avenues for further investigations are also reviewed.