Perfect as the enemy of good: tracing transmissions with low-sensitivity tests to mitigate SARS-CoV-2 outbreaks.
Perfect as the enemy of good: tracing transmissions with low-sensitivity tests to mitigate SARS-CoV-2 outbreaks.
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DOI：
10.1016/s2666-5247(21)00004-5
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发表时间：
2021-05
期刊：
影响因子：
--
通讯作者：
Hanage WP
中科院分区：
文献类型：
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作者：
Kennedy-Shaffer L;Baym M;Hanage WP
在整个新冠肺炎大流行期间，各国政府和个人尝试了各种战略，以限制该大流行对人类生命、人口健康和经济造成的损害。接触者追踪一直是一种常用的策略，已经提出并尝试了各种方法。我们总结了一些接触者追踪和检测的方法，考虑到每种方法所需的资源以及SARS-CoV-2传播的特点如何影响其有效性。我们还提出了一种专注于跟踪传播事件的方法，当超级传播事件在传播中扮演重要角色时，这种方法可以特别有效。考虑到关于病原体的最佳可用证据和资源的可用性可以使控制策略更有效，即使它们并不完美。
Throughout the COVID-19 pandemic, governments and individuals have attempted a wide variety of strategies to limit the damage of the pandemic on human lives, population health, and economies. Contact tracing has been a commonly used strategy, and various approaches have been proposed and attempted. We summarise some methods of contact tracing and testing, considering the resources demanded by each and how features of SARS-CoV-2 transmission affect their effectiveness. We also propose an approach focusing on tracing transmission events, which can be particularly effective when superspreading events play a large role in transmission. Accounting for the best available evidence on a pathogen and for the availability of resources can make control strategies more effective, even if they are not perfect.