Screening for hepatitis C among HIV positive patients at Mulago hospital in Uganda.
Screening for hepatitis C among HIV positive patients at Mulago hospital in Uganda.
复制标题
乌干达穆拉戈医院对艾滋病毒阳性患者进行丙型肝炎筛查。
DOI：
10.4314/ahs.v9i3.48996
复制
发表时间：
2009
影响因子：
1
通讯作者：
M. Kagimu
中科院分区：
文献类型：
--
作者：
Walusansa;M. Kagimu
背景
BACKGROUND
In industrialized countries with more resources, it is recommended that HIV infected patients should be screened for hepatitis C virus (HCV) on entry into the health care system. Implementation of these guidelines in a country like Uganda with limited resources requires some modification after taking into account the prevailing circumstances. These include the prevalence of HCV in HIV positive patients and the cost of HCV testing.
OBJECTIVE
The objective of the study was to estimate the prevalence of HCV in HIV positive patients.
METHODS
This was a cross sectional study among HIV positive outpatients in Mulago hospital. HCV screening was done using anti-HCV Enzyme Immuno Assay (Roche Diagnostics)
RESULTS
Between October 2003 and February 2004, one hundred and twenty two HIV positive patients were enrolled into the study with a mean age of 33.9 years. There were more females 81 (66.4%) than males. Only 4 patients had anti-HCV, giving an estimated HCV prevalence of 3.3%.
CONCLUSION
In view of the low HCV prevalence found in our study and similar studies and considering the high cost of HCV screening, routine HCV testing cannot be recommended among all HIV positive patients in our health care settings with limited resources. We recommend that HCV screening be limited to investigating HIV positive patients with features suggestive of liver disease in order to identify HCV as a possible cause.
影响因子：
120.7
作者：
Sulkowski, MS;Thomas, DL;Moore, RD
通讯作者：
Moore, RD