A pilot randomised control trial of a parent training intervention for pre-school children with autism - Preliminary findings and methodological challenges

A pilot randomised control trial of a parent training intervention for pre-school children with autism - Preliminary findings and methodological challenges
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DOI:
10.1007/s00787-002-0299-6
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发表时间:
2002-12-01
影响因子:
6.4
通讯作者:
Charman, T
Charman, T
中科院分区:
医学2区
文献类型:
--
作者:
Drew, A;Baird, G;Charman, T

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很少有人尝试对患有自闭症的学龄前儿童进行干预的随机对照试验(RCT)。我们报告了一项针对家长培训干预的试点随机对照试验的结果,重点是发展联合注意力技能和联合行动程序。24名符合ICD-10儿童自闭症标准的儿童(平均年龄=23个月)通过聊天屏幕被识别出来,并被随机分配到父母训练组或只接受当地服务。12个月后进行随访(平均年龄35个月)。有一些证据表明,家长培训小组在语言发展方面比当地服务小组取得了更大的进步。然而,目前的初步研究受到几个因素的影响:依赖父母的报告来衡量语言,群体的初始智商不匹配,以及缺乏对父母培训干预实施的系统检查。此外,在研究过程中,当地服务小组中的三名父母开始了密集的、以家庭为基础的行为干预。讨论了在为患有自闭症的学龄前儿童进行随机对照试验时遇到的困难。强调了未来用于自闭症干预的设计良好的随机对照试验的方法学挑战和战略。
Few attempts have been made to conduct randomised control trials (RCTs) of interventions for pre-school children with autism. We report findings of a pilot RCT for a parent training intervention with a focus on the development of joint attention skills and joint action routines. Twenty-four children meeting ICD-10 criteria for childhood autism (mean age = 23 months) were identified using the CHAT screen and randomised to the parent training group or to local services only. A follow-up was conducted 12 months later (mean age = 35 months). There was some evidence that the parent training group made more progress in language development than the local services group. However, the present pilot study was compromised by several factors: a reliance on parental report to measure language, non-matching of the groups on initial IQ, and a lack of systematic checking regarding the implementation of the parent training intervention. Furthermore, three parents in the local services group commenced intensive, home-based behavioural intervention during the course of the study. The difficulties encountered in the conduct of RCTs for pre-school children with autism are discussed. Methodological challenges and strategies for future well-designed RCTs for autism interventions are highlighted.