Aerobic interval training increases peak oxygen uptake more than usual care exercise training in myocardial infarction patients: a randomized controlled study
Aerobic interval training increases peak oxygen uptake more than usual care exercise training in myocardial infarction patients: a randomized controlled study
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DOI：
10.1177/0269215511405229
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发表时间：
2012-01-01
影响因子：
3
通讯作者：
Slordahl, Stig A.
中科院分区：
文献类型：
--
作者：
Moholdt, Trine;Aamot, Inger Lise;Slordahl, Stig A.
目的：运动能力强预测生存和有氧间歇训练（AIT）增加心脏病患者有效的峰值摄氧量。挪威的心脏护理在心肌梗死（MI）后在医院提供运动训练，但这些康复计划的效果和实际强度尚不清楚。设计：随机对照试验。设置：医院心脏康复。受试者：107例患者，在MI后2至12周招募，随机接受常规护理康复或跑步机AIT。干预措施：有氧运动训练或跑步机AIT为434分钟的间隔，峰值心率为85-95%。每周两次运动训练，共12周。主要指标：主要结果指标为峰值摄氧量。次要结局指标为内皮功能、心血管疾病的血液标志物、生活质量、静息心率和心率recovery.Results：89例患者（74例男性，15例女性，57.4 +/- 9.5岁）完成了该计划。AIT后的峰值摄氧量（从31.6 +/- 5.8增加到36.2 +/- 8.6 mL.kg（-1）.min（-1），P < 0.001）比常规护理康复后（从32.2 +/- 6.7增加到34.7 +/- 7.9 mL.kg（-1）.min（-1），P < 0.001）增加更多（P= 0.002）。与常规护理组的最高强度相比，AIT组在间歇期的运动强度显著更高（峰值心率分别为87.3 +/- 3.9%和78.7 +/- 7.2%，P < 0.001）。这两个程序增加内皮功能，血清脂联素和生活质量，降低血清铁蛋白和静息心率。高密度脂蛋白胆固醇增加后AIT.Conclusions：AIT增加峰值摄氧量比通常的护理康复提供给MI患者的挪威医院。
Objective: Exercise capacity strongly predicts survival and aerobic interval training (AIT) increases peak oxygen uptake effectively in cardiac patients. Usual care in Norway provides exercise training at the hospitals following myocardial infarction (MI), but the effect and actual intensity of these rehabilitation programmes are unknown.Design: Randomized controlled trial.Setting: Hospital cardiac rehabilitation.Subjects: One hundred and seven patients, recruited two to 12 weeks after MI, were randomized to usual care rehabilitation or treadmill AIT.Interventions: Usual care aerobic group exercise training or treadmill AIT as 434 minutes intervals at 85-95% of peak heart rate. Twice weekly exercise training for 12 weeks.Main measures: The primary outcome measure was peak oxygen uptake. Secondary outcome measures were endothelial function, blood markers of cardiovascular disease, quality of life, resting heart rate, and heart rate recovery.Results: Eighty-nine patients (74 men, 15 women, 57.4 +/- 9.5 years) completed the programme. Peak oxygen uptake increased more (P=0.002) after AIT (from 31.6 +/- 5.8 to 36.2 +/- 8.6 mL.kg(-1).min(-1), P < 0.001) than after usual care rehabilitation (from 32.2 +/- 6.7 to 34.7 +/- 7.9 mL.kg(-1).min(-1), P < 0.001). The AIT group exercised with significantly higher intensity in the intervals compared to the highest intensity in the usual care group (87.3 +/- 3.9% versus 78.7 +/- 7.2% of peak heart rate, respectively, P < 0.001). Both programmes increased endothelial function, serum adiponectin, and quality of life, and reduced serum ferritin and resting heart rate. High-density lipoprotein cholesterol increased only after AIT.Conclusions: AIT increased peak oxygen uptake more than the usual care rehabilitation provided to MI patients by Norwegian hospitals.