Cardiovascular risk assessment in South and Middle-East Asians living in the Western countries.

Cardiovascular risk assessment in South and Middle-East Asians living in the Western countries.
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DOI:
10.12669/pjms.36.7.3292
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发表时间:
2020-11
影响因子:
2.2
通讯作者:
Nilsson PM
Nilsson PM
中科院分区:
医学4区
文献类型:
--
作者:
Saeed S;Kanaya AM;Bennet L;Nilsson PM

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近四分之一的世界人口生活在南亚地区(印度,巴基斯坦,孟加拉国,斯里兰卡,尼泊尔,不丹和马尔代夫)。由于这些国家的人口和流行病迅速转变,非传染性疾病的负担日益加重,这是一个严重的公共卫生问题。特别是糖尿病前期、糖尿病和动脉粥样硬化性心血管疾病(CVD)的患病率正在增加。生活在西方的南亚人与白色欧洲人和美国人相比,患心血管疾病的风险和死亡率也高得多。此外,由于过去30年来全球流离失所的现象,中东移民现在是北方最大的非欧洲移民群体。对这一弱势群体的研究较少。因此,本综述的目的是解决南亚人(主要是来自印度,巴基斯坦和孟加拉国的人)和生活在西方国家的中东亚洲人与白人(高加索人)相比的心血管风险评估,并介绍一些主要干预研究的结果。在PubMed中进行了系统检索,以确定与本综述相关的南亚和中东人群的主要心血管健康研究。结果表明CVD的风险增加。总之,生活在西方的南亚和中东人群与本土白色欧洲人相比,患糖尿病和心血管疾病的风险明显更高。生活方式干预已被证明在降低糖尿病风险方面具有有益效果,可提高胰岛素敏感性、减轻体重以及更好地控制血糖和血脂。
Nearly a quarter of the world population lives in the South Asian region (India, Pakistan, Bangladesh, Sri Lanka, Nepal, Bhutan, and the Maldives). Due to rapid demographic and epidemiological transition in these countries, the burden of non-communicable diseases is growing, which is a serious public health concern. Particularly, the prevalence of pre-diabetes, diabetes and atherosclerotic cardiovascular disease (CVD) is increasing. South Asians living in the West have also substantially higher risk of CVD and mortality compared with white Europeans and Americans. Further, as a result of global displacement over the past three decades, Middle-Eastern immigrants now represent the largest group of non-European immigrants in Northern Europe. This vulnerable population has been less studied. Hence, the aim of the present review was to address cardiovascular risk assessment in South Asians (primarily people from India, Pakistan and Bangladesh), and Middle-East Asians living in Western countries compared with whites (Caucasians) and present results from some major intervention studies. A systematic search was conducted in PubMed to identify major cardiovascular health studies of South Asian and Middle-Eastern populations living in the West, relevant for this review. Results indicated an increased risk of CVD. In conclusion, both South Asian and Middle-Eastern populations living in the West carry significantly higher risk of diabetes and CVD compared with native white Europeans. Lifestyle interventions have been shown to have beneficial effects in terms of reduction in the risk of diabetes by increasing insulin sensitivity, weight loss as well as better glycemic and lipid control.
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