Effects of physical training on plasma citrate and exercise-induced asthma.
Effects of physical training on plasma citrate and exercise-induced asthma.
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体育训练对血浆柠檬酸盐和运动诱发哮喘的影响。
DOI：
10.3109/00365518109092038
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发表时间：
1981
影响因子：
2.1
通讯作者：
R. Dahl
中科院分区：
文献类型：
--
作者：
J. Henriksen;T. T. Nielsen;R. Dahl
对7名哮喘儿童在6周运动训练前后进行6 min跑台运动，测定其血浆枸橼酸水平。静息血浆柠檬酸盐浓度从训练前的116 +/- 9 mumol/l（平均值+/- SE）增加至训练后的158 +/- 11 mumol/l（p <0.02）。运动期间的血浆乳酸增加通过训练降低（p <0.02）;个体变化与训练诱导的静息血浆柠檬酸盐浓度升高呈负相关（r =-0.77，p <0.05）。运动后呼气峰流速下降百分比从训练前的32 +/- 13%下降到训练后的15 +/- 8%（p <0.05）。结果同意的假设，增加柠檬酸盐浓度的组织，通过诱导磷酸果糖激酶的抑制，可能是调节的重要性，减少乳酸积累耐力training. In man.此外，训练对运动诱发的哮喘的有益影响被证明。
Plasma citrate was determined in seven asthmatic children exposed to 6 min treadmill running before and after 6 weeks of physical training. Resting plasma citrate concentration increased from 116 +/- 9 mumol/l (mean +/- SE) before to 158 +/- 11 mumol/l after training (p less than 0.02). Plasma lactate increase during exercise was lowered by training (p less than 0.02); the individual change correlated inversely with the training-induced rise in resting plasma citrate concentration (r = -0.77, p less than 0.05). The postexercise percentage fall in peak expiratory flow rate decreased from 32 +/- 13% before to 15 +/- 8% after training (p less than 0.05). The results agree with the hypothesis that an increased citrate concentration of tissues, by inducing an inhibition of phosphofructokinase, may be of regulatory importance for the decreased lactate accumulation following endurance training in man. In addition, a beneficial effect of training on exercise-induced asthma is demonstrated.