Genetic parameters for resistance to Infectious Pancreatic Necrosis in pedigreed Atlantic salmon (Salmo salar) post-smolts using a Reduced Animal Model
Genetic parameters for resistance to Infectious Pancreatic Necrosis in pedigreed Atlantic salmon (Salmo salar) post-smolts using a Reduced Animal Model
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DOI：
10.1016/j.aquaculture.2009.02.015
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发表时间：
2009-05-19
期刊：
影响因子：
4.5
通讯作者：
Brotherstone, Sue
中科院分区：
文献类型：
--
作者：
Guy, Derrick R.;Bishop, Stephen C.;Brotherstone, Sue
传染性胰腺坏死病毒（IPNV）是所有商业养殖鲑鱼物种死亡和经济损失的重要原因，并且先前已经证明了IPN挑战的存活遗传变异。为了在抗性菌株的开发中利用这种变异，需要稳健的程序来量化遗传变异的程度，并提供用于选择育种候选物的估计育种值。本文采用了最近开发的实施减少动物混合模型程序（RAM），以现场数据描述的百分比死亡率以下IPN流行病在苏格兰养殖的大西洋鲑鱼，涵盖1369全同胞家庭组分布在四年，共7个网站。通过电子（PIT）标记和使用微卫星DNA分析的亲子关系分配相结合，建立了谱系。遗传力在0.07和0.56之间（s.e.
Infectious Pancreatic Necrosis Virus (IPNV) is an important cause of mortality and economic loss across all species of commercially farmed salmonids, and genetic variation in survival to IPN challenge has been previously demonstrated. In order to exploit this variation in the development of resistant strains, robust procedures are required to quantify the extent of genetic variation and to provide estimated breeding values used to select candidates for breeding. This paper applies a recently developed implementation of the Reduced-Animal Mixed-model procedure (RAM) to field data describing percent mortality following IPN epidemics in Scottish farmed Atlantic salmon, covering 1369 full-sib family groups distributed over four years and a total of seven sites. Pedigrees were established through a combination of electronic (PIT) tagging and parentage assignment using microsatellite DNA analysis. Heritabilities between 0.07 and 0.56 (s.e.