Cortical activation during fast repetitive finger movements in humans: steady-state movement-related magnetic fields and their cortical generators
Cortical activation during fast repetitive finger movements in humans: steady-state movement-related magnetic fields and their cortical generators
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DOI：
10.1016/s0924-980x(98)00045-9
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发表时间：
1998-10-01
期刊：
影响因子：
--
通讯作者：
Shibasaki, H
中科院分区：
文献类型：
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作者：
Gerloff, C;Uenishi, N;Shibasaki, H
目的：研究快速重复滞留运动的皮质生理学。方法：在122道全头磁力仪上记录与自控、重复、2赫兹手指运动相关的稳态运动相关磁场。结果：肌电起始附近有两个主要的SSMRMF成分：运动场CMF在EMG起始后37+/-11ms达到峰值；运动后保持(后MF)，极性相反，在EMG起始后102+/-13ms达到峰值。MF的ECD位于初级运动皮质(M1)，而MF术后的ECD位于初级躯体感觉皮质(S1)。MF可能与皮质脊髓抽动的发生密切相关，而MF后的MF很可能代表再传入反馈过程。结论：本研究数据进一步证明，皮层活动的主要相位变化发生在对侧M1和S1的重复EMG爆发的直接附近。它们通过提供更精确的解剖学信息，补充了以往脑电图(EEC)关于稳态运动相关皮质电位(SsMRCP)的发现，从而增强了ssMRCP和ssMRMFS在非侵入性和高时间分辨率研究人类感觉运动皮质激活方面的潜在价值。(C)1998爱思唯尔爱尔兰科学有限公司。保留所有权利。
Objective: To study the cortical physiology of fast repetitive linger movements.Methods: We recorded steady-state movement-related magnetic fields (ssMRMFs) associated with self-paced, repetitive, 2-Hz finger movements in a 122-channel whole-head magnetometer. The ssMRMF generators were determined by equivalent current dipole (ECD) modeling and co-registered with anatomical magnetic resonance images (MRIs).Results: Two major ssMRMF components occurred in proximity to EMG onset: a motor field CMF) peaking at 37 +/- 11 ms after EMG onset, and a postmovement held (post-MF), with inverse polarity, peaking at 102 +/- 13 ms after EMG onset. The ECD for the MF was located in the primary motor cortex (M1), and the ECD for the post-MF in the primary somatosensory cortex (S1). The MF was probably closely related to the generation of corticospinal volleys, whereas the post-MF most likely represented reafferent feedback processing.Conclusions: The present data offer further evidence that the main phasic changes of cortical activity occur in direct proximity to repetitive EMG bursts in the contralateral M1 and S1. They complement previous electroencephalography (EEC) findings on steady-state movement-related cortical potentials (ssMRCPs) by providing more precise anatomical information, and thereby enhance the potential value of ssMRCPs and ssMRMFs for studying human sensorimotor cortex activation non-invasively and with high temporal resolution. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.