Regulation of Cerebral Blood Flow: Response to Cytochrome P450 Lipid Metabolites.
Regulation of Cerebral Blood Flow: Response to Cytochrome P450 Lipid Metabolites.
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DOI：
10.1002/cphy.c170025
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发表时间：
2018-03
影响因子：
5.8
通讯作者：
D. Harder;K. Rarick;D. Gebremedhin;Susan S. Cohen
中科院分区：
文献类型：
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作者：
D. Harder;K. Rarick;D. Gebremedhin;Susan S. Cohen
有很多关于脑循环的评论。这些评论在很多方面都是相似的。在目前的综述中，我们认为重要的是提供功能概述，特别关注与脑内平衡，神经元能量需求维持相关的脑动脉控制细节，以及与星形胶质细胞作用相关的独特视角。接下来的回顾将讨论脑血管的发育以及新生儿循环和发育中的大脑的独特特性，因此，这里遗漏了发育的许多方面。同样，最近在本系列中也发表了关于大脑和脑循环对热应激反应的综述(8)。为了使这篇综述具有独特性，一些明显的主题没有被讨论，而代替了其他一些来自最近和具有挑衅性的研究，如内皮衍生的超极化因子，影响脑血流的蛋白质的昼夜节律调节，以及神经血管单元的独特特性。©2018美国生理学会。物理学报（英文版），2018。
There have been numerous reviews related to the cerebral circulation. Most of these reviews are similar in many ways. In the present review, we thought it important to provide an overview of function with specific attention to details of cerebral arterial control related to brain homeostasis, maintenance of neuronal energy demands, and a unique perspective related to the role of astrocytes. A coming review in this series will discuss cerebral vascular development and unique properties of the neonatal circulation and developing brain, thus, many aspects of development are missing here. Similarly, a review of the response of the brain and cerebral circulation to heat stress has recently appeared in this series (8). By trying to make this review unique, some obvious topics were not discussed in lieu of others, which are from recent and provocative research such as endothelium-derived hyperpolarizing factor, circadian regulation of proteins effecting cerebral blood flow, and unique properties of the neurovascular unit. © 2018 American Physiological Society. Compr Physiol 8:801-821, 2018.