Effect of Chronic Obstructive Pulmonary Disease on In-Hospital Mortality and Clinical Outcomes After ST-Segment Elevation Myocardial Infarction
Effect of Chronic Obstructive Pulmonary Disease on In-Hospital Mortality and Clinical Outcomes After ST-Segment Elevation Myocardial Infarction
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DOI：
10.1016/j.amjcard.2017.02.024
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发表时间：
2017-05-15
影响因子：
2.8
通讯作者：
Reed, Guy
中科院分区：
文献类型：
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作者：
Agarwal, Manyoo;Agrawal, Sahil;Reed, Guy
关于ST段抬高（STEMI）和慢性阻塞性肺疾病（COPD）患者的住院死亡率、血运重建和其他不良结局存在争议。我们查询了2003年至2011年全国住院患者样本数据库，以确定年龄≥ 18岁且初步诊断为STEMI的患者。进行单因素和多因素分析，以评估COPD与住院临床结局的相关性。COPD患者占2例患者的13.2%; 120，005例STEMI患者。COPD与年龄较大、医疗保险、合并症较多和社会经济地位较低有关。与非COPD患者相比，即使调整了多种潜在的其他因素，COPD患者的住院死亡率也更高（12.5% vs 8.6%，调整后优势比[AOR] 1.13，95%CI 1.11 - 1.15，p
There is controversy regarding in-hospital mortality, revascularization, and other adverse outcomes in patients with ST-segment elevation (STEMI) and chronic obstructive pulmonary disease (COPD). We queried the 2003 to 2011 Nationwide Inpatient Sample databases to identify patients aged >= 18 years with a primary diagnosis of STEMI. Univariate and multivariate analyses were performed to evaluate the association of COPD with in-hospital clinical outcomes. Patients with COPD comprised 13.2% of 2;120,005 patients with STEMI. COPD was associated with older age, Medicare insurance, greater co-morbidities, and lower socioeconomic status. Compared with non-COPD patients, patients with COPD had higher inpatient mortality even after adjustment for multiple potential other factors (12.5% vs 8.6%, adjusted odds ratio [AOR] 1.13, 95% CI 1.11 to 1.15, p