Thermodilution method overestimates low cardiac output in humans.
Thermodilution method overestimates low cardiac output in humans.
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DOI：
10.1152/ajpheart.1983.245.4.h690
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发表时间：
1983-10
期刊：
影响因子：
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通讯作者：
A. Grondelle;R. Ditchey;B. Groves;W. Wagner;J. Reeves
中科院分区：
文献类型：
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作者：
A. Grondelle;R. Ditchey;B. Groves;W. Wagner;J. Reeves
我们比较了26例患者用热稀释法和菲克法测量的57个心输出量，发现菲克输出量小于3.5 l/min的16例患者的热稀释值都更高。在10个菲克值小于或等于2.5升/分钟的情况下，热稀释和菲克测量值平均相差35%。当结合先前比较热稀释、染料稀释和菲克技术的研究结果时，这些发现表明热稀释法在低输出范围内高估了真正的心输出量。这种高估可能是由于低流量条件下的热损失。由于热稀释法广泛用于低输出状态的患者，因此这些发现具有潜在的重要临床意义。
We compared 57 cardiac output measurements by the thermodilution and Fick methods in 26 patients and found that thermodilution values were higher in all 16 cases in which Fick outputs were less than 3.5 l/min. In 10 cases where Fick values were less than or equal to 2.5 l/min, thermodilution and Fick measurements differed by an average of 35%. When combined with the results of previous studies comparing the thermodilution, dye dilution, and Fick techniques, these findings suggest that the thermodilution method overestimates true cardiac output in the low output range. This overestimation probably is due to heat loss under conditions of low flow. Because the thermodilution method is used widely in patients with low output states, these findings have potentially important clinical implications.