Moth olfactory receptor neurons adjust their encoding efficiency to temporal statistics of pheromone fluctuations.
Moth olfactory receptor neurons adjust their encoding efficiency to temporal statistics of pheromone fluctuations.
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DOI：
10.1371/journal.pcbi.1006586
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发表时间：
2018-11
影响因子：
4.3
通讯作者：
Lucas P
中科院分区：
文献类型：
--
作者：
Levakova M;Kostal L;Monsempès C;Jacob V;Lucas P
有效编码假说预测，感觉神经元调整其编码资源，以最佳地代表其环境的刺激统计。为了测试这一预测蛾嗅觉系统，我们已经开发了一个刺激协议，模仿自然的时间结构内的湍流信息素羽。我们报告说，触角嗅觉受体神经元的信息素遇到的反应遵循这样一种方式，最频繁的刺激时间尺度编码的最大精度的时间波动。我们还观察到，在距信息素源给定距离处调整到刺激时间尺度统计数据的神经元的平均编码精度高于在较短、非匹配距离处应用相同编码模型的情况。最后，编码的准确性配置文件和刺激的时间尺度分布相关的方式预测的信息理论的多对一的收敛方案的蛾外周感觉系统。生物体的感觉神经系统以惊人的效率编码其环境的表征。我们研究了信息素特异性触角神经元对自然嗅觉刺激的动态编码。分析表明，从几个互补的信息理论的角度来看，表示是最佳的。(1)如果浓度遵循自然间歇的时间过程，则最好检测信息素遭遇。(2)脑神经元动态地适应局部刺激统计。(3)编码准确度分布和刺激时间尺度分布的关系预测的信息理论和统计估计理论。
The efficient coding hypothesis predicts that sensory neurons adjust their coding resources to optimally represent the stimulus statistics of their environment. To test this prediction in the moth olfactory system, we have developed a stimulation protocol that mimics the natural temporal structure within a turbulent pheromone plume. We report that responses of antennal olfactory receptor neurons to pheromone encounters follow the temporal fluctuations in such a way that the most frequent stimulus timescales are encoded with maximum accuracy. We also observe that the average coding precision of the neurons adjusted to the stimulus-timescale statistics at a given distance from the pheromone source is higher than if the same encoding model is applied at a shorter, non-matching, distance. Finally, the coding accuracy profile and the stimulus-timescale distribution are related in the manner predicted by the information theory for the many-to-one convergence scenario of the moth peripheral sensory system. Sensory neural systems of living organisms encode the representation of their environment with remarkable efficiency. We study the dynamic coding of naturalistic olfactory stimulation by pheromone-specific antennal neurons. The analysis reveals that the representation is optimal from several complementary information-theoretic perspectives. (1) Pheromone encounters are best detected if the concentration follows the naturally intermittent time course. (2) Antennal neurons dynamically adjust to the local stimulus statistics. (3) The coding accuracy profile and the stimulus-timescale distribution are in the relationship predicted by both information theory and statistical estimation theory.
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影响因子：
3.4
作者：
Garcia-Lazaro, J. A.;Ho, S. S. M.;Schnupp, J. W. H.
通讯作者：
Schnupp, J. W. H.
影响因子：
2.8
作者：
Dolzer, J;Fischer, K;Stengl, M
通讯作者：
Stengl, M
嗅觉感觉神经元中果蝇化学感受器的独特信号传导
DOI：
10.1073/pnas.1518329113
发表时间：
2016-02-16
影响因子：
11.1
作者：
Cao, Li-Hui;Jing, Bi-Yang;Luo, Dong-Gen
通讯作者：
Luo, Dong-Gen
影响因子：
7.7
作者：
Gorur-Shandilya, Srinivas;Demir, Mahmut;Emonet, Thierry
通讯作者：
Emonet, Thierry
影响因子：
13.6
作者：
JONES, CD
通讯作者：
JONES, CD