Plant nuclei move to escape ultraviolet-induced DNA damage and cell death.
Plant nuclei move to escape ultraviolet-induced DNA damage and cell death.
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植物细胞核移动是为了逃避紫外线引起的 DNA 损伤和细胞死亡。
DOI：
10.1104/pp.15.01400
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发表时间：
2016
期刊：
影响因子：
7.4
通讯作者：
Hara-Nishimura I.
中科院分区：
文献类型：
--
作者：
Iwabuchi K.;Hidema J.;Tamura K.;Takagi S.;Hara-Nishimura I.
植物细胞核的一个显著特征是它们依赖于光的运动。在拟南芥叶肉细胞中，细胞核在蓝光照射后1~3h内移至细胞侧壁，但原因不明。在这里，我们表明，核运动是一种快速而有效的策略，以避免紫外线B(UVB)诱导的损伤。叶肉细胞核在黑暗中位于细胞底部，但突然暴露在紫外线下会造成严重的DNA损伤和细胞死亡。在蓝光处理的叶片和肌动蛋白细胞骨架缺陷的突变叶片中，损伤都显著减轻。有趣的是，在强光条件下生长的植物，即使在黑暗中，叶肉核也会留在侧壁上。这些结果表明，植物有两种减少UVB暴露的策略：针对急性暴露的快速核移动和针对慢性暴露的核锚定。
A striking feature of plant nuclei is their light-dependent movement. In Arabidopsis (Arabidopsis thaliana) leaf mesophyll cells, the nuclei move to the side walls of cells within 1 to 3 h after blue-light reception, although the reason is unknown. Here, we show that the nuclear movement is a rapid and effective strategy to avoid ultraviolet B (UVB)-induced damages. Mesophyll nuclei were positioned on the cell bottom in the dark, but sudden exposure of these cells to UVB caused severe DNA damage and cell death. The damage was remarkably reduced in both blue-light-treated leaves and mutant leaves defective in the actin cytoskeleton. Intriguingly, in plants grown under high-light conditions, the mesophyll nuclei remained on the side walls even in the dark. These results suggest that plants have two strategies for reducing UVB exposure: rapid nuclear movement against acute exposure and nuclear anchoring against chronic exposure.