The interaction of sarin and soman with plasma proteins: the identification of a novel phosphonylation site
The interaction of sarin and soman with plasma proteins: the identification of a novel phosphonylation site
复制标题
DOI：
10.1007/s002040050596
复制
发表时间：
1999-03-01
影响因子：
6.1
通讯作者：
Read, RW
中科院分区：
文献类型：
--
作者：
Black, RM;Harrison, JM;Read, RW
将沙林和梭曼与人血浆一起孵育表明，结合发生在酪氨酸残基上。当沙林和梭曼与人血清白蛋白一起孵育时，也会发生类似的结合。这种结合可提供一种重要的生物标记，在指控使用化学武器的情况下，这种标记保留了关于制剂身份的全部结构信息。
Incubation of both sarin and soman with human plasma has shown that binding occurs to a tyrosine residue. Similar binding occurs when sarin and soman are incubated with human serum albumin. This binding may provide an important biological marker, which retains full structural information concerning the identity of the agent, in cases of allegations of chemical warfare use.