SMALL HEPATOCELLULAR-CARCINOMA - TREATMENT WITH SUBSEGMENTAL TRANSCATHETER ARTERIAL EMBOLIZATION
SMALL HEPATOCELLULAR-CARCINOMA - TREATMENT WITH SUBSEGMENTAL TRANSCATHETER ARTERIAL EMBOLIZATION
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DOI：
10.1148/radiology.188.1.8390073
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发表时间：
1993-07-01
期刊：
影响因子：
19.7
通讯作者：
KOGAYASHI, K
中科院分区：
文献类型：
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作者：
MATSUI, O;KADOYA, M;KOGAYASHI, K
回顾性分析了亚段经导管动脉栓塞（TAE）治疗小肝癌（HCC）的疗效。对100例肝硬化患者进行了TAE。直径小于4cm的结节型肝癌共124例。TAE通过将碘化油和抗癌药物的混合物，然后将明胶海绵颗粒或碘化油和无水乙醇的混合物注射到亚段动脉的更远侧分支中进行。在11个切除病灶中，7个在组织学检查中观察到完全坏死。在90例未手术随访的其余113个病灶中，TAE后1年和4年局部复发率分别为18%和33%。82例Child A、B级患者1、4年生存率分别为100%和67%。未观察到肝功能实质性恶化。亚段TAE可改善肝硬化合并小肝癌患者的预后。
The effectiveness of subsegmental transcatheter arterial embolization (TAE) therapy for small hepatocellular carcinomas (HCCs) was retrospectively analyzed. TAE was performed in 100 patients with liver cirrhosis. There was a total of 124 nodular-type HCCs less than 4 cm in diameter. TAE was performed by injecting a mixture of iodized oil and anticancer drugs followed by gelatin sponge particles or a mixture of iodized oil and absolute ethanol into the more distal branches of the subsegmental artery. Complete necrosis was seen at histologic examination in seven of 11 resected lesions. Among the remaining 113 lesions in 90 patients followed up without surgery, the 1- and 4-year local recurrence rates after TAE were 18% and 33%, respectively. The 1- and 4-year survival rates for 82 patients with Child class A or B disease were 100% and 67%, respectively. No substantial deterioration of liver function was observed. Subsegmental TAE improved the prognosis of the patients with liver cirrhosis associated with small HCCs.